SecurityPTI / Proteostasis Therapeutics, Inc. (74373B109)
President and CEOChhabra Meenu
IndustryPharmaceutical Preparations
Institutional Owners64
Institutional Shares23,975,939 - 65.33%
Common Shares Outstanding36,696,948 shares (as of 2018-06-30)
Institutional Value$ 74,492,000 USD

Institutional Stock Ownership and Shareholders

PTI / Proteostasis Therapeutics, Inc. Institutional Ownership

Proteostasis Therapeutics, Inc. (NASDAQ:PTI) has 64 institutional investors and shareholders that have filed 13D/G or 13F forms with the Securities Exchange Commission (SEC). These institutions hold a total of 23,975,939 shares. Largest shareholders include NEA Management Company, LLC, Wellington Management Group LLP, Jennison Associates Llc, BlackRock Inc., Vanguard Group Inc, Rtw Investments, Llc, Hillhouse Capital Management, Ltd., FIL Ltd, Bailard, Inc., and Rock Springs Capital Management LP.
Proteostasis Therapeutics, Inc. (NASDAQ:PTI) ownership structure shows current positions in the company by institutions and funds, as well as latest changes in position size. Major shareholders can include individual investors, mutual funds, hedge funds, or institutions. The Schedule 13D indicates that the investor holds more than 5% of the company and intends to actively pursue a change in business strategy. Schedule 13G indicates a passive investment of over 5%. Green rows indicate new positions. Red rows indicate closed positions. Click the link icon to see the full transaction history.

File DateFormInvestor Opt Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
($1000)
Current Value
($1000)
Change
(Percent)
2018-08-14 13F-HR VANGUARD GROUP INC 950,327 1,085,885 14.26 4,514 3,030 -32.88
2018-08-02 13F-HR JENNISON ASSOCIATES LLC 3,621,854 3,663,710 1.16 17,204 10,222 -40.58
2018-08-01 13F-HR WELLS FARGO & COMPANY/MN 6,000 33,745 462.42 29 94 224.14
2018-08-14 13F-HR TWO SIGMA ADVISERS, LP 50,400 141
2018-08-14 13F-HR/A CITADEL ADVISORS LLC 0 70,425 0 196
2018-08-14 13F-HR Rock Springs Capital Management LP 675,000 471,321 -30.17 3,206 1,315 -58.98
2017-02-10 13F-HR BlackRock Japan Co. Ltd 201 0 -100.00 3 0 -100.00
2018-08-14 13F-HR HARBOURVEST PARTNERS LLC 440,627 440,627 0.00 2,093 1,229 -41.28
2018-08-14 13F-HR CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0 38,515 0 107
2018-08-14 13F-HR BRIDGEWAY CAPITAL MANAGEMENT INC 138,845 138,845 0.00 660 387 -41.36
2018-08-10 13F-HR Cutler Group LP Put 10,200 4,400 -56.86 34 11 -67.65
2018-08-14 13F-HR Endurant Capital Management LP 472,012 0 -100.00 2,242 0 -100.00
2018-08-15 13F-HR GRANAHAN INVESTMENT MANAGEMENT INC/MA 70,534 81,693 15.82 335 228 -31.94
2017-02-10 13F-HR BlackRock Fund Advisors 215,224 253,809 17.93 3,355 3,112 -7.24
2018-08-09 13F-HR BlackRock Inc. 47,654 1,807,717 3,693.42 226 5,043 2,131.42
2018-10-16 13F-HR ESSEX INVESTMENT MANAGEMENT CO LLC 96,900 96,900 0.00 270 234 -13.33
2018-08-14 13F-HR Tower Research Capital LLC (TRC) 0 200 0 1
2018-08-15 13F-HR CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM 41,200 41,200 0.00 196 115 -41.33
2018-08-14 13F-HR/A CITADEL ADVISORS LLC Put 19,700 55
2018-08-06 13F-HR RHUMBLINE ADVISERS 22,663 63
2017-02-10 13F-HR BlackRock Institutional Trust Company, N.A. 52,807 55,270 4.66 823 678 -17.62
2018-08-10 13F-HR CITIGROUP INC 0 3,864 0 11
2018-08-10 13F-HR DIMENSIONAL FUND ADVISORS LP 37,027 37,027 0.00 176 103 -41.48
2018-08-14 13F-HR Squarepoint Ops LLC 0 20,962 0 58
2018-08-10 13F-HR Legal & General Group Plc 0 3,748 0 10
2018-08-10 13F-HR Cutler Group LP 2,000 2,200 10.00 9 6 -33.33
2018-08-14 13F-HR/A CITADEL ADVISORS LLC Call 12,200 34
2018-08-14 13F-HR Wellington Management Group LLP 4,827,560 5,043,780 4.48 22,931 14,072 -38.63
2018-08-14 13F-HR GOLDMAN SACHS GROUP INC 41,468 41,936 1.13 197 117 -40.61
2018-08-14 13F-HR BANK OF AMERICA CORP /DE/ 4,045 222 -94.51 19 1 -94.74
2018-08-09 13F-HR NEA Management Company, LLC 5,556,778 5,556,778 0.00 26,395 15,503 -41.27
2018-08-14 13F-HR LORD, ABBETT & CO. LLC 481,093 0 -100.00 2,285 0 -100.00
2018-08-14 13F-HR STATE STREET CORP 13,400 210,200 1,468.66 63 588 833.33
2018-08-14 13F-HR Dynamic Technology Lab Private Ltd 0 28,102 0 78
2018-07-27 13F-HR PIEDMONT INVESTMENT ADVISORS LLC 437 1
2018-07-30 13F-HR SIMPLEX TRADING, LLC 1,853 5
2018-08-14 13F-HR MANUFACTURERS LIFE INSURANCE COMPANY, THE 1,327 1,327 0.00 6 4 -33.33
2018-08-10 13F-HR NEW YORK STATE COMMON RETIREMENT FUND 0 400 0 1
2018-08-14 13F-HR Cubist Systematic Strategies, LLC 34,512 96
2018-08-14 13F-HR MILLENNIUM MANAGEMENT LLC 212,891 0 -100.00 1,011 0 -100.00
2018-08-07 13F-HR Trexquant Investment LP 31,296 0 -100.00 149 0 -100.00
2018-10-12 13F-HR BANK OF MONTREAL /CAN/ 179 177 -1.12 0 0
2018-08-08 13F-HR BAILARD, INC. 520,100 582,400 11.98 2,470 1,625 -34.21
2018-08-14 13F-HR JP Morgan Chase & Co 212,493 217,604 2.41 1,009 607 -39.84
2018-08-08 13F-HR AMERICAN INTERNATIONAL GROUP INC 0 16,395 0 46
2018-08-14 13F-HR Hillhouse Capital Management, Ltd. 865,923 865,923 0.00 4,113 2,416 -41.26
2018-07-24 13F-HR ACADIAN ASSET MANAGEMENT LLC 50,607 141
2018-08-10 13F-HR DOHENY ASSET MANAGEMENT /CA 69,625 0 -100.00 331 0 -100.00
2018-08-14 13F-HR SUSQUEHANNA INTERNATIONAL GROUP, LLP Call 220,100 45,600 -79.28 1,045 127 -87.85
2018-08-14 13F-HR RTW INVESTMENTS, LLC 1,104,940 1,077,408 -2.49 5,248 3,006 -42.72
2018-08-14 13F-HR DEUTSCHE BANK AG\ 20 45,552 227,660.00 0 126
2018-08-14 13F-HR Jefferies Group LLC 0 11,700 0 33
2018-08-14 13F-HR TWO SIGMA INVESTMENTS LLC 62,223 95,797 53.96 296 267 -9.80
2018-08-14 13F-HR Alyeska Investment Group, L.P. 79,945 76,277 -4.59 380 213 -43.95
2018-08-10 13F-HR FIL Ltd 652,316 652,316 0.00 3,099 1,820 -41.27
2018-08-14 13F-HR Invesco Ltd. 10,268 29
2017-02-10 13F-HR BlackRock Investment Management, LLC 32,586 33,673 3.34 508 413 -18.70
2018-08-14 13F-HR SUSQUEHANNA INTERNATIONAL GROUP, LLP Put 180,400 96,900 -46.29 857 270 -68.49
2018-08-13 13F-HR Bayesian Capital Management, LP 33,500 18,100 -45.97 159 50 -68.55
2018-08-10 13F-HR Cutler Group LP Call 14,600 6,000 -58.90 3 0 -100.00
2017-02-10 13F-HR BlackRock Advisors LLC 2,894 2,894 0.00 45 35 -22.22
2018-08-08 13F-HR SCHWAB CHARLES INVESTMENT MANAGEMENT INC 18,300 46,900 156.28 87 131 50.57
2018-08-14 13F-HR TIAA CREF INVESTMENT MANAGEMENT LLC 0 38,603 0 108
2018-07-31 13F-HR TD ASSET MANAGEMENT INC 21,200 0 -100.00 101 0 -100.00
2018-08-13 13F-HR Ameritas Investment Partners, Inc. 0 2,293 0 6
2018-08-14 13F-HR BlueCrest Capital Management Ltd 77,572 0 -100.00 368 0 -100.00
2018-08-14 13F-HR ROYAL BANK OF CANADA 10,550 14,253 35.10 50 39 -22.00
2018-08-14 13F-HR PRICE T ROWE ASSOCIATES INC /MD/ 768,804 135,079 -82.43 3,652 377 -89.68
2018-08-23 13F-HR/A BROOKSIDE CAPITAL MANAGEMENT LLC 399,947 0 -100.00 1,900 0 -100.00
2018-08-10 13F-HR Tibra Equities Europe Ltd 52,987 0 -100.00 252 0 -100.00
2018-08-13 13F-HR ALLIANCEBERNSTEIN L.P. 21,400 60
2018-08-14 13F-HR ELEMENT CAPITAL MANAGEMENT LLC 33,360 0 -100.00 158 0 -100.00
2018-08-14 13F-HR UBS Group AG 2,504 10,731 328.55 12 30 150.00
2018-08-10 13F-HR DAFNA Capital Management LLC 267,100 0 -100.00 1,269 0 -100.00
2018-08-14 13F-HR CREDIT SUISSE AG/ 16,961 0 -100.00 81 0 -100.00
2018-09-18 13F-HR/A NORTHERN TRUST CORP 43,034 269,451 526.14 204 752 268.63
2018-08-14 13F-HR SUSQUEHANNA INTERNATIONAL GROUP, LLP 20,682 0 -100.00 98 0 -100.00
2018-08-14 13F-HR FRANKLIN RESOURCES INC 110,400 0 -100.00 524 0 -100.00
2018-08-14 13F-HR GEODE CAPITAL MANAGEMENT, LLC 168,141 233,193 38.69 798 650 -18.55
2018-07-25 13F-HR BNP PARIBAS ARBITRAGE, SA 0 823 0 2,296
2018-08-14 13F-HR TEACHERS ADVISORS INC 0 35,759 0 100
2018-08-14 13F-HR MORGAN STANLEY 25,966 54,895 111.41 123 153 24.39
2018-07-24 13F-HR MEEDER ASSET MANAGEMENT INC 451 743 64.75 2 2,074 103,600.00
2018-08-14 13F-HR BARCLAYS PLC 54,957 14,452 -73.70 261 40 -84.67
PTI: Proteostasis Therapeutics Analysis and Research Report

2018-08-31 - Asif

Overview Proteostasis Therapeutics is an innovative, clinical stage biopharmaceutical company committed to the discovery and development of novel therapeutics to treat cystic fibrosis, or CF, and other diseases caused by an imbalance in the proteostasis network, a set of pathways that control protein biosynthesis, folding, trafficking and clearance. The Company focuses on identifying therapies that restore protein function. CF is a disease caused by defects in the function or abundance of cystic fibrosis transmembrane conductance regulator, or CFTR. The company's CF focused pipeline consists of novel CFTR modulators including correctors, potentiators and amplifiers. Upon discovery of amplifiers, a novel class of CFTR modulators, Proteostasis Therapeutics has exploited its novel mechanism of action as a drug screening tool and have subsequently identified correctors and potentiators to be developed as part of combination therapies. Investigational agents representative of all th...

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CUSIP: 74373B109