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SecurityINSM / Insmed, Inc. (457669307)
President & CEOLewis William
IndustryPharmaceutical Preparations
Institutional Owners141
Institutional Shares88,224,158 - 115.14%
Institutional Value$ 4,060,605,000 USD

Institutional Stock Ownership and Shareholders()

Insmed, Inc. (NASDAQ:INSM) has 141 institutional investors and shareholders that have filed 13D/G or 13F forms with the Securities Exchange Commission (SEC). These institutions hold a total of 88,224,158 shares. Largest shareholders include Price T Rowe Associates Inc /md/, FMR LLC / Fidelity, BlackRock Inc., Palo Alto Investors, LLC, Vanguard Group Inc, Henderson Group Plc, State Street Corp, Orbimed Advisors Llc, Janus Capital Management Llc, and BlackRock Fund Advisors.
Insmed, Inc. (NASDAQ:INSM) ownership structure shows current positions in the company by institutions and funds, as well as latest changes in position size. Major shareholders can include individual investors, mutual funds, hedge funds, or institutions. The Schedule 13D indicates that the investor holds more than 5% of the company and intends to actively pursue a change in business strategy. Schedule 13G indicates a passive investment of over 5%. Green rows indicate new positions. Red rows indicate closed positions. Click the link icon to see the full transaction history.

File DateFormInvestor Opt Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
($1000)
Current Value
($1000)
Change
(Percent)
2018-05-03 13F-HR SG Americas Securities, LLC 0 5,138 0 116
2018-05-15 13F-HR Metlife Investment Advisors, Llc 33,492 33,492 0.00 1,044 754 -27.78
2018-05-11 13F-HR Cutler Group LP Call 3,100 0 -100.00 44 0 -100.00
2018-05-14 13F-HR Pacer Advisors, Inc. 625 0 -100.00 19 0 -100.00
2018-05-15 13F-HR ORBIMED ADVISORS LLC 1,496,791 2,927,891 95.61 46,670 65,936 41.28
2018-05-15 13F-HR GEODE CAPITAL MANAGEMENT, LLC 691,982 731,229 5.67 21,575 16,467 -23.68
2018-05-14 13F-HR TIAA CREF INVESTMENT MANAGEMENT LLC 244,624 244,311 -0.13 7,627 5,502 -27.86
2018-05-15 13F-HR Adage Capital Partners GP LLC 720,034 890,000 23.61 22,451 20,043 -10.73
2018-04-26 13F-HR MOODY ALDRICH PARTNERS LLC 31,046 0 -100.00 968 0 -100.00
2018-05-15 13F-HR Crestline Management, LP 68,856 0 -100.00 2,147 0 -100.00
2017-02-10 13F-HR BlackRock Fund Advisors 2,392,925 2,705,488 13.06 34,745 35,794 3.02
2018-05-21 13F-HR Winton Capital Group Ltd 21,256 479
2018-05-03 13F-HR CAM Group Holding A/S 392,007 372,662 -4.93 12,223 8,392 -31.34
2018-02-09 13F-HR RidgeWorth Capital Management LLC 0 11,494 0 358
2018-05-11 13F-HR CITIGROUP INC 65,397 72,886 11.45 2,039 1,641 -19.52
2018-05-02 13F-HR THOMPSON DAVIS & CO., INC. 500 500 0.00 16 11 -31.25
2018-05-03 13F-HR DekaBank Deutsche Girozentrale 35,100 34,400 -1.99 411 758 84.43
2018-05-02 13F-HR Daiwa Securities Group Inc. 423 10
2018-05-15 13F-HR TWO SIGMA INVESTMENTS LLC 116,127 95,885 -17.43 3,621 2,159 -40.38
2018-05-15 13F-HR WOLVERINE TRADING, LLC Put 21,000 42,000 100.00 655 946 44.43
2018-05-15 13F-HR Foresite Capital Management Iv, Llc 879,910 1,799,225 104.48 27,436 40,519 47.69
2018-04-26 13F-HR EMERALD ADVISERS INC/PA 859,011 726,946 -15.37 26,784 16,371 -38.88
2018-05-15 13F-HR Ameritas Investment Partners, Inc. 6,347 6,347 0.00 198 143 -27.78
2018-05-01 13F-HR ALPS ADVISORS INC 84,871 102,752 21.07 2,646 2,314 -12.55
2018-05-15 13F-HR OBERWEIS ASSET MANAGEMENT INC/ 10,000 0 -100.00 312 0 -100.00
2018-05-15 13F-HR BARCLAYS PLC Put 0 100 0 2
2018-05-15 13F-HR/A Sabby Management, LLC Put 0 543 0 1,223
2018-05-14 13F-HR ALLIANCEBERNSTEIN L.P. 152,800 181,800 18.98 4,764 4,094 -14.06
2018-05-08 13F-HR US BANCORP \DE\ 1,413 681 -51.80 44 15 -65.91
2018-05-14 13F-HR DLD Asset Management, LP Put 0 110,000 0 2,477
2018-05-15 13F-HR DEUTSCHE BANK AG\ 430,424 272,145 -36.77 13,419 6,127 -54.34
2018-05-07 13F-HR SYNOVUS FINANCIAL CORP 0 50 0 1
2018-05-15 13F-HR TUDOR INVESTMENT CORP ET AL 9,022 15,066 66.99 281 339 20.64
2018-05-14 13F-HR UBS ASSET MANAGEMENT AMERICAS INC 45,939 53,504 16.47 1,432,378 1,204,911 -15.88
2018-05-14 13F-HR BOOTHBAY FUND MANAGEMENT, LLC Put 583 1,313
2018-05-15 13F-HR Parallax Volatility Advisers, L.P. 11,424 0 -100.00 356 0 -100.00
2018-05-14 13F-HR FMR LLC / Fidelity 11,488,651 11,492,691 0.04 358,216 258,816 -27.75
2018-05-18 13F-HR/A ROYAL BANK OF CANADA 500 107 -78.60 15 2 -86.67
2018-05-14 13F-HR VIRTUS ETF ADVISERS LLC 11,494 24,409 112.36 358 550 53.63
2018-05-15 13F-HR MANUFACTURERS LIFE INSURANCE COMPANY, THE 58,088 56,876 -2.09 1,811 1,281 -29.27
2018-05-22 13F-HR AMALGAMATED BANK 10,402 10,181 -2.12 324 229 -29.32
2018-05-11 13F-HR ADVENT CAPITAL MANAGEMENT /DE/ 50 1
2018-05-15 13F-HR QS Investors, LLC 75,620 71,511 -5.43 2,358 1,610 -31.72
2018-04-20 13F-HR FIRST MANHATTAN CO 25 25 0.00 0 0
2018-05-15 13F-HR DRIEHAUS CAPITAL MANAGEMENT LLC 33,108 0 -100.00 1,032 0 -100.00
2018-04-26 13F-HR SIMPLEX TRADING, LLC Call 3 1 -66.67 2 0 -100.00
2018-05-15 13F-HR Foresite Capital Management Iv, Llc Put 300,000 6,800
2018-05-11 13F-HR BNP PARIBAS ARBITRAGE, SA Put 10,500 236,460
2018-05-15 13F-HR J. Goldman & Co LP 19,894 265,123 1,232.68 620 5,971 863.06
2018-05-15 13F-HR Wellington Management Group LLP 81,758 137,340 67.98 2,549 3,093 21.34
2018-05-09 13F-HR Bellevue Group AG 334,489 7,533
2018-05-11 13F-HR Private Ocean, LLC 2,500 2,500 0.00 78 56 -28.21
2018-04-26 13F-HR EMERALD MUTUAL FUND ADVISERS TRUST 697,332 628,779 -9.83 21,743 14,160 -34.88
2018-05-15 13F-HR CREDIT SUISSE AG/ 63,087 82,153 30.22 1,967 1,850 -5.95
2018-05-15 13F-HR GOLDMAN SACHS GROUP INC 301,740 345,433 14.48 9,408 7,779 -17.32
2017-08-11 13F-HR FT Options LLC Put 85,000 107,600 26.59 91 121 32.97
2018-05-16 13F-HR/A GROUP ONE TRADING, L.P. Put 6,700 49,200 634.33 209 1,108 430.14
2018-05-03 13F-HR Zurcher Kantonalbank (Zurich Cantonalbank) 4,662 4,662 0.00 145 105 -27.59
2018-05-25 13F-HR/A Worth Venture Partners, LLC Put 0 11,700 0 26
2018-05-15 13F-HR J. Goldman & Co LP Call 32,500 0 -100.00 1,013 0 -100.00
2018-05-14 13F-HR BOOTHBAY FUND MANAGEMENT, LLC 14,440 0 -100.00 450 0 -100.00
2018-05-14 13F-HR UNIVERSITY OF NOTRE DAME DU LAC 87,121 90,753 4.17 2,716 2,044 -24.74
2018-05-02 13F-HR RHUMBLINE ADVISERS 74,574 73,219 -1.82 2,325 1,649 -29.08
2018-05-14 13F-HR MORGAN STANLEY 351,517 670,020 90.61 10,960 15,089 37.67
2018-05-14 13F-HR Renaissance Technologies LLC 36,487 0 -100.00 1,138 0 -100.00
2017-02-10 13F-HR BlackRock Japan Co. Ltd 91 0 -100.00 1 0 -100.00
2018-05-14 13F-HR ProShare Advisors LLC 52,620 45,207 -14.09 1,641 1,018 -37.96
2018-05-11 13F-HR Quantbot Technologies LP 1,635 4,841 196.09 50 109 118.00
2018-05-03 13F-HR MACKAY SHIELDS LLC 28,908 651
2018-05-15 13F-HR BARCLAYS PLC 27,361 39,665 44.97 853 894 4.81
2018-05-16 13F-HR/A GROUP ONE TRADING, L.P. Call 8,300 35,400 326.51 259 797 207.72
2018-05-15 13F-HR Advisor Group, Inc. 45 45 0.00 1 1 0.00
2018-05-14 13F-HR HENDERSON GROUP PLC 5,963,206 6,246,342 4.75 185,933 140,668 -24.34
2018-05-15 13F-HR SUSQUEHANNA INTERNATIONAL GROUP, LLP Put 113,800 369,900 225.04 3,548 8,330 134.78
2018-05-14 13F-HR PARAMETRIC PORTFOLIO ASSOCIATES LLC 60,585 29,584 -51.17 1,889 666 -64.74
2018-04-26 13F-HR SIMPLEX TRADING, LLC Put 28 1 -96.43 2 0 -100.00
2018-05-15 13F-HR SUSQUEHANNA INTERNATIONAL GROUP, LLP Call 119,200 201,700 69.21 3,717 4,542 22.20
2018-05-15 13F-HR BARCLAYS PLC Call 0 100 0 2
2018-05-11 13F-HR CITIGROUP INC Put 35,700 10,200 -71.43 1,113 230 -79.34
2018-05-10 13F-HR NEW YORK STATE COMMON RETIREMENT FUND 78,800 82,100 4.19 2,457 1,849 -24.75
2018-05-15 13F-HR VANGUARD GROUP INC 6,305,495 6,428,289 1.95 196,604 144,764 -26.37
2018-05-17 13F-HR Legal & General Group Plc 34,666 29,657 -14.45 1,082 668 -38.26
2018-05-15 13F-HR SPRINGBOK CAPITAL MANAGEMENT, LLC 83,806 87,338 4.21 2,613 1,967 -24.72
2018-05-15 13F-HR/A Sabby Management, LLC 0 13,300 0 300
2018-05-04 13F-HR Swiss National Bank 119,600 126,900 6.10 3,729 2,858 -23.36
2018-05-15 13F-HR Alyeska Investment Group, L.P. 313,537 424,017 35.24 9,776 9,549 -2.32
2018-05-14 13F-HR Lazarus Management Co LLC 8,325 0 -100.00 259 0 -100.00
2018-05-11 13F-HR SEI INVESTMENTS CO 20,749 14,919 -28.10 647 336 -48.07
2018-05-14 13F-HR Crawford Lake Capital Management, LLC 249,008 0 -100.00 7,764 0 -100.00
2018-05-04 13F-HR STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 34,921 35,620 2.00 1,089 802 -26.35
2018-05-09 13F-HR BlackRock Inc. 7,830,604 7,725,860 -1.34 244,159 173,986 -28.74
2018-05-15 13F-HR EARNEST PARTNERS LLC 1,130 1,130 0.00 35 25 -28.57
2018-02-14 13F-HR CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. 40,808 33,408 -18.13 1,272 1,041 -18.16
2018-05-15 13F-HR MILLENNIUM MANAGEMENT LLC 23,389 0 -100.00 729 0 -100.00
2018-05-15 13F-HR Bank of New York Mellon Corp 420,220 382,583 -8.96 13,103 8,616 -34.24
2018-05-14 13F-HR BOOTHBAY FUND MANAGEMENT, LLC Call 583 1,313
2018-05-08 13F-HR Aperio Group, LLC 11,527 0 -100.00 359 0 -100.00
2018-05-14 13F-HR/A CITADEL ADVISORS LLC Call 8,800 0 -100.00 274 0 -100.00
2018-05-11 13F-HR GSA CAPITAL PARTNERS LLP 19,824 0 -100.00 618 0 -100.00
2018-05-15 13F-HR Baker Brothers Advisors LP 700,000 700,000 0.00 21,826 15,764 -27.77
2018-04-26 13F-HR BP PLC 12,276 0 -100.00 383 0 -100.00
2018-05-10 13F-HR GREAT WEST LIFE ASSURANCE CO /CAN/ 10,775 10,775 0.00 335 243 -27.46
2018-05-15 13F-HR D. E. Shaw & Co., Inc. 507,325 293,978 -42.05 15,818 6,620 -58.15
2018-05-11 13F-HR CITADEL ADVISORS LLC Put 21,000 473
2018-05-09 13F-HR NORTHERN TRUST CORP 953,984 957,164 0.33 29,746 21,555 -27.54
2018-05-15 13F-HR LORD, ABBETT & CO. LLC 700,571 799,733 14.15 21,844 18,010 -17.55
2018-05-11 13F-HR Gemmer Asset Management LLC 3 3 0.00 0 0
2018-05-15 13F-HR Endurant Capital Management LP 22,910 0 -100.00 714 0 -100.00
2018-05-11 13F-HR BNP PARIBAS ARBITRAGE, SA 16,183 16,243 0.37 504,586 365,792 -27.51
2018-05-15 13F-HR HBK INVESTMENTS L P 46,275 98,252 112.32 1,443 2,213 53.36
2018-05-15 13F-HR Omega Advisors Inc. 155,000 98,000 -36.77 4,833 2,207 -54.33
2018-05-08 13F-HR/A CHARTWELL INVESTMENT PARTNERS, LLC 105,163 52,628 -49.96 3,279 1,185 -63.86
2017-08-11 13F-HR FT Options LLC 8,475 17,958 111.89 148 308 108.11
2018-05-14 13F-HR/A CITADEL ADVISORS LLC Put 18,000 21,000 16.67 561 473 -15.69
2018-04-27 13F-HR LOS ANGELES CAPITAL MANAGEMENT & EQUITY RESEARCH INC 0 74,280 0 1,673
2017-05-01 13F-HR Spot Trading L.L.C Call 20,000 350
2018-05-15 13F-HR TWO SIGMA ADVISERS, LP 0 9,300 0 209
2018-04-13 13F-HR BANK OF MONTREAL /CAN/ 952 684 -28.15 30 15 -50.00
2018-04-20 13F-HR Seacrest Wealth Management, Llc 100 100 0.00 3 2 -33.33
2018-05-15 13F-HR Jefferies Group LLC 7,865 8,965 13.99 245 202 -17.55
2018-05-15 13F-HR WOLVERINE TRADING, LLC 11,085 25,807 132.81 110 581 428.18
2018-05-15 13F-HR Redmile Group, LLC 2,249,262 2,166,362 -3.69 70,132 48,786 -30.44
2018-05-15 13F-HR Tower Research Capital LLC (TRC) 192 4,034 2,001.04 6 91 1,416.67
2018-05-04 13F-HR VICTORY CAPITAL MANAGEMENT INC 598,250 589,460 -1.47 18,653 13,274 -28.84
2018-05-03 13F-HR MEEDER ASSET MANAGEMENT INC 176 0 -100.00 5 0 -100.00
2018-04-25 13F-HR RICE HALL JAMES & ASSOCIATES, LLC 261,712 5,894
2018-05-14 13F-HR AMERIPRISE FINANCIAL INC 285,746 322,588 12.89 8,910 7,266 -18.45
2018-04-20 13F-HR STRS OHIO 1,900 0 -100.00 59 0 -100.00
2018-05-15 13F-HR Foresite Capital Management II, LLC 518,645 967,636 86.57 16,171 21,791 34.75
2018-05-15 13F-HR SECOR Capital Advisors, LP 0 16,649 0 375
2018-05-08 13F-HR TEACHER RETIREMENT SYSTEM OF TEXAS 23,598 16,103 -31.76 736 363 -50.68
2018-05-10 13F-HR JP Morgan Chase & Co Put 40,000 901
2018-05-07 13F-HR STATE OF WISCONSIN INVESTMENT BOARD 74,200 74,200 0.00 2,314 1,671 -27.79
2018-07-11 13F-HR Xact Kapitalforvaltning AB 15,481 13,781 -10.98 349 326 -6.59
2018-05-15 13F-HR Voya Investment Management LLC 683,139 798,615 16.90 21,300 17,985 -15.56
2018-05-15 13F-HR Clearbridge Investments, LLC 1,376 1,376 0.00 43 31 -27.91
2018-05-15 13F-HR SECTORAL ASSET MANAGEMENT INC 90,199 0 -100.00 2,812 0 -100.00
2018-05-04 13F-HR PRUDENTIAL FINANCIAL INC 7,320 0 -100.00 228 0 -100.00
2018-05-14 13F-HR TEACHERS ADVISORS INC 255,863 259,384 1.38 7,978 5,841 -26.79
2018-05-11 13F-HR CITIGROUP INC Call 39,900 7,300 -81.70 1,244 164 -86.82
2018-05-11 13F-HR Cutler Group LP Put 300 0 -100.00 0 0
2018-05-15 13F-HR Palo Alto Investors, LLC 6,404,586 7,159,590 11.79 199,695 161,234 -19.26
2018-05-15 13F-HR METROPOLITAN LIFE INSURANCE CO/NY 24,316 24,931 2.53 758 561,446 73,969.39
2018-05-14 13F-HR PRICE T ROWE ASSOCIATES INC /MD/ 13,028,622 12,580,281 -3.44 406,232 283,308 -30.26
2018-05-15 13F-HR Invesco Ltd. 132,301 137,785 4.15 4,125 3,103 -24.78
2018-04-25 13F-HR PICTET ASSET MANAGEMENT LTD 0 65,100 0 1,466
2018-04-10 13F-HR NISA INVESTMENT ADVISORS L.L.C. 800 450 -43.75 25 10 -60.00
2017-02-10 13F-HR BlackRock Group LTD 26,681 29,032 8.81 387 384 -0.78
2018-05-15 13F-HR BANK OF AMERICA CORP /DE/ 24,458 35,974 47.08 762 810 6.30
2018-05-15 13F-HR PointState Capital LP 226,000 5,090
2018-05-11 13F-HR TD ASSET MANAGEMENT INC 260,795 259,895 -0.35 8,132 5,853 -28.03
2018-05-08 13F-HR Smith Asset Management Group LP 0 7,390 0 166
2017-02-10 13F-HR BlackRock Advisors LLC 38,990 32,506 -16.63 566 430 -24.03
2018-05-11 13F-HR Russell Investments Group, Ltd. 57,926 26,529 -54.20 1,014 598 -41.03
2018-05-14 13F-HR BROWN BROTHERS HARRIMAN & CO 975 22
2018-05-15 13F-HR NEXTHERA CAPITAL LP 498,921 918,523 84.10 15,556 20,685 32.97
2018-05-15 13F-HR WOLVERINE TRADING, LLC Call 20,500 19,800 -3.41 639 446 -30.20
2018-05-15 13F-HR AQR CAPITAL MANAGEMENT LLC 95,932 99,003 3.20 2,991 2,230 -25.44
2017-08-11 13F-HR FT Options LLC Call 61,500 70,000 13.82 152 141 -7.24
2018-05-14 13F-HR UNITED SERVICES AUTOMOBILE ASSOCIATION 11,760 265
2018-05-14 13F-HR Hudson Bay Capital Management LP 120,000 190,000 58.33 3,742 4,279 14.35
2018-04-11 13F-HR FRANKLIN STREET ADVISORS INC /NC 15,700 15,700 0.00 490 354 -27.76
2018-05-15 13F-HR CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 120,610 116,525 -3.39 3,761 2,624 -30.23
2018-05-15 13F-HR Rock Springs Capital Management LP 613,500 825,000 34.47 19,129 18,579 -2.88
2017-02-10 13F-HR BlackRock Institutional Trust Company, N.A. 1,547,283 1,562,321 0.97 22,467 20,670 -8.00
2018-05-15 13F-HR UBS Group AG 20,670 117,567 468.78 645 2,647 310.39
2018-05-10 13F-HR CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM 86,600 147,600 70.44 2,700 3,324 23.11
2018-05-15 13F-HR STATE STREET CORP 2,912,319 3,461,180 18.85 90,805 77,944 -14.16
2018-05-15 13F-HR Weiss Multi-Strategy Advisers LLC 50,000 70,000 40.00 1,559 1,576 1.09
2018-05-15 13F-HR HIGHLAND CAPITAL MANAGEMENT LP 0 20,000 0 450
2018-05-15 13F-HR JANE STREET GROUP, LLC 11,916 13,464 12.99 372 303 -18.55
2018-05-22 13F-HR/A Summit Trail Advisors, Llc 12,178 250
2018-05-09 13F-HR FEDERATED INVESTORS INC /PA/ 44,565 1,016 -97.72 1,390 23 -98.35
2017-02-10 13F-HR BlackRock Investment Management, LLC 235,774 235,336 -0.19 3,423 3,113 -9.06
2018-05-15 13F-HR GUGGENHEIM CAPITAL LLC 95,779 103,962 8.54 2,986 2,342 -21.57
2018-05-07 13F-HR SCHWAB CHARLES INVESTMENT MANAGEMENT INC 361,662 381,444 5.47 11,277 8,591 -23.82
2018-05-10 13F-HR JP Morgan Chase & Co Call 0 40,000 0 901
2018-05-01 13F-HR PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 6,021 6,021 0.00 188 136 -27.66
2018-04-18 13F-HR/A FNY Managed Accounts LLC 107 0 -100.00 3 0 -100.00
2018-05-02 13F-HR WELLS FARGO & COMPANY/MN 43,763 58,400 33.45 1,364 1,315 -3.59
2017-05-16 13F-HR JANUS CAPITAL MANAGEMENT LLC 2,855,576 2,809,457 -1.62 37,784 49,191 30.19
2018-05-08 13F-HR Asymmetry Capital Management, L.P. 158,277 162,185 2.47 4,935 3,652 -26.00
2018-05-14 13F-HR EAM Investors, LLC 85,424 0 -100.00 2,664 0 -100.00
2018-05-10 13F-HR JP Morgan Chase & Co 207,190 218,794 5.60 6,461 4,928 -23.73
2018-05-07 13F-HR AMERICAN INTERNATIONAL GROUP INC 51,539 48,909 -5.10 1,607 1,101 -31.49
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Your Daily Pharma Scoop: Loxo Outstanding Results, Cimzia Trial Success, Audentes Positive Data

2018-05-17 seekingalpha
Loxo Oncology (NASDAQ:LOXO), which was recently covered in a series of excellent articles by our very own Dr. Zach Hartman, PhD, who collaborates with the Total Pharma Tracker and whose members saw an early view of the series (...and so on), is up strongly “following preliminary results which showed that its new LOXO-292 experimental cancer drug led to tumor shrinkage in nearly 70% of patients regardless of where their cancer originated. (114-0)

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