Publicly Traded Drugs Companies - SIC Code 283

List of Sub-Industries

Member Companies

This list is made from self-reported SIC codes that companies file with the SEC.

ExchangeTickerCountryNameCUSIPCIKMarket Cap
OTC ENDV US Endonovo Therapeutics, Inc. 29272H102 1528172 15,759,398
OTC AXIM US Axim Biotechnologies, Inc. 05463V100 1514946
OTC PRTT US Protect Pharmaceutical Corp 74364W203 1493526
OTC NNAB US NanoAntibiotics, Inc. 63009U102 1580149 12,502,412
OTC BIVI US BioVie, Inc. 09074F108 1580149
NASDAQ BSPM US Biostar Pharmaceuticals, Inc. 090678202 1418133 8,755,464
AMEX IBIO US iBio Inc. 451033104 1420720 16,441,687
OTC GLUC US Glucose Health, Inc. 1420108 570,779
OTC SGBI US Sangui BioTech International, Inc. 80105B101 1104280
OTC SKVI US Skinvisible, Inc. 830703104 1085277 0
OTC GTHR US GeneThera, Inc. 37185E306 1017110 248,190
OTC ONDR US Online Disruptive Technologies, Inc. 1498380
OTC JSHY US Jishanye Inc. 1569737 359,991,006
OTC HSTC US HST Global, Inc. 797564
OTC IMMD US ImmuDyne, Inc. 45252N109 948320
AMEX HEB US Hemispherx BioPharma, Inc. 42366C103 946644
AMEX PTN US Palatin Technologies, Inc. 696077403 911216 184,245,073
OTC ABMC US American Bio Medica Corp. 024600108 896747
OTC RCPI US Rock Creek Pharmaceuticals, Inc. 772081105 776008 620,000
OTC RCPIQ US Rock Creek Pharmaceuticals, Inc. 776008
OTC MRNA US Marina Biotech, Inc. 56804Q201 737207
OTC RGRX US RegeneRx Biopharmaceuticals, Inc. 75886X108 707511 33,133,655
NASDAQ ABEOW US Abeona Therapeutics Inc. Warrants 00289Y115 318306 470,402,418
NASDAQ ABEO US Abeona Therapeutics Inc. 00289Y107 318306
OTC EMIS US Emisphere Technologies, Inc. 291345106 805326
AMEX OCX US OncoCyte Corporation 04624N107 1642380 125,311,050
NASDAQ WVE US WAVE Life Sciences Ltd. Y95308105 1631574 1,096,472,284
OTC TLCC US Twinlab Consolidated Holdings, Inc. 1590695 0
AMEX AST US Asterias Biotherapeutics, Inc. 68235C107 1572552 114,473,300
AMEX AST.WS US Asterias Biotherapeutics, Inc. Warrants 04624N115 1572552
OTC IMUN US Immune Therapeutics, Inc. 45252A107 1559356
OTC PPCB US Propanc Biopharma, Inc. 74345C102 1517681
OTC PPCH US Propanc Health Group Corp. 74346N107 1517681 45,456
OTC BIEI US Premier Biomedical Inc 74048K104 1515740
OTC RZLT US Rezolute, Inc. 1509261
OTC ANTB US AntriaBio, Inc. 037230109 1509261 52,887,981
NASDAQ XBIO US Xenetic Biosciences, Inc. 984015206 1534525
OTC SGTH US Signpath Pharma, Inc. 826712101 1455694
OTC ERGO US Entia Biosciences Inc. 29384E104 1408299
OTC FPMI US FluoroPharma Medical, Inc. 343870101 1402785
NASDAQ SNDX US Syndax Pharmaceuticals, Inc. 87164F105 1395937 251,534,355
NASDAQ CLDN US Celladon Corporation 28249U105 1305253 9,628,874
NASDAQ EIGR US Eiger BioPharmaceuticals, Inc. 15117E107 1305253 75,356,406
OTC FTLF US FitLife Brands, Inc. 33817P108 1374328 43,541,950
AMEX OGEN US Oragenics, Inc. 684023203 1174940 133,040,391
OTC FTCY US Global Future City Holding Inc. 1164964
OTC AOLS US Aeolus Pharmaceuticals, Inc. 00765G109 1261734
AMEX CPHI US China Pharma Holdings, Inc. 16941T104 1106644
NASDAQ ARGS US Argos Therapeutics, Inc. 040221103 1105533 133,942,788
NASDAQ IMNP US Immune Pharmaceuticals Inc. 45254C101 1208261
OTC ARNI US Arno Therapeutics, Inc. 042564203 1195116 1,341,175
NASDAQ TPIV US TapImmune, Inc. 876033408 1094038 38,832,724
OTC TPIVD US TapImmune, Inc. 1094038 63,154,273
AMEX AXN US Aoxing Pharmaceutical Company, Inc. 03740A106 1060426 9,297,522
OTC TRUU US True Drinks Holdings, Inc. 897837100 1134765
OTC PKTX US ProtoKinetix, Inc. 743722100 1128189 22,243,328
NASDAQ DFFN US Diffusion Pharmaceuticals Inc. 001053691 1053691
OTC RESX US RestorGenex Corporation 1053691
OTC AMAR US Amarillo Biosciences, Inc. 02301P205 1014763
AMEX VNRX US VolitionRX Ltd 928661107 93314 95,974,146
AMEX IMUC.WS US ImmunoCellular Therapeutics, Ltd., Warrants 452536121 822411 0
AMEX IMUC US ImmunoCellular Therapeutics, Ltd. 452536105 822411 4,210,808
NASDAQ CASI US CASI Pharmaceuticals, Inc. 14757U109 895051
NASDAQ ADMP US Adamis Pharmaceuticals Corp. 00547W208 887247
OTC CAPS US Capstone Therapeutics Corp 14068E109 887151
NASDAQ PRPH US ProPhase Labs, Inc. 74345W108 868278 38,001,460
NASDAQ AVXS US AveXis, Inc. 05366U100 1652923 3,632,032,146
NASDAQ XBIT US XBiotech Inc. 98400H102 1626878 167,551,287
NASDAQ CRBP US Corbus Pharmaceuticals Holdings, Inc. 21833P103 1595097 446,972,213
NASDAQ CTRV US Contravir Pharmaceuticals Inc 21234W103 1583771 24,045,805
AMEX MTNB US Matinas Biopharma Holdings, Inc. 576810105 1582554
OTC CLCS US Cell Source, Inc. 1569340 8,080,509
OTC ENUM US Enumeral Biomedical Holdings, Inc. 294017108 1561551 12,967,705
OTC DDRT US DanDrit Biotech USA, Inc. 236078101 1527728
TSXV COB.U CA Cohbar Inc 1522602
NASDAQ CWBR US CohBar Inc. 19249J109 1522602 253,040,822
NASDAQ NTRP US Neurotrope, Inc. 64129T207 1513856 54,945,024
OTC GNSZ US GenSpera, Inc. 1421204
OTC NSPX US Inspyr Therapeutics, Inc. 45782A205 1421204
NASDAQ MYOS US MYOS RENS Technology Inc. 62857P108 1402479
NASDAQ EYEGW US Eyegate Pharmaceuticals Inc. Warrants 30233M115 1372514
NASDAQ EYEG US Eyegate Pharmaceuticals Inc. 30233M107 1372514 19,957,542
NASDAQ ADMA US ADMA Biologics Inc 000899104 1368514 101,615,772
NASDAQ PTI US Proteostasis Therapeutics, Inc. 74373B109 1445283
OTC PRGB US Protea Biosciences Group Inc 74365B109 1335103 0
NASDAQ CAPR US Capricor Therapeutics, Inc. 14070B101 1133869 48,860,315
NASDAQ CYCCP US Cyclacel Pharmaceuticals Inc., 6.00% Convertible Exchangeable Preferred Stock 23254L207 1130166 61,963,278
NASDAQ CYCC US Cyclacel Pharmaceuticals, Inc. 23254L306 1130166
EPA OXI FR OXIS International 109657
OTC GTBP US GT Biopharma Inc. 36254L100 109657
OTC OXISD US OXIS International, Inc. 691829501 109657
OTC INBP US Integrated BioPharma, Inc. 45811V105 1016504 4,438,387
NASDAQ CPIX US Cumberland Pharmaceuticals Inc. 230770109 1087294 111,546,128
NASDAQ GNVC US GenVec, Inc. 37246C307 934473 16,350,060
OTC MYMX US Mymetics Corp. 62856A102 927761
AMEX APHB US Ampliphi Biosciences Corp. 03211P202 921114 10,206,035
NASDAQ SNGX US Soligenix, Inc. 834223307 812796 12,840,280
NASDAQ GBT US Global Blood Therapeutics, Inc. 37890U108 1629137 2,602,037,572
NASDAQ ZYNE US Zynerba Pharmaceuticals, Inc. 98986X109 1621443 158,103,892
NASDAQ NEOT US Neothetics, Inc. 64066G101 1618835 26,556,954
NASDAQ REPH US Recro Pharma, Inc. 75629F109 1588972 166,765,865
NASDAQ ZSAN US Zosano Pharma Corporation 98979H103 1587221 290,679,480
NASDAQ CLTX US Celsus Therapeutics 15119A202 1541157
NASDAQ AKTX US Akari Therapeutics Plc 00972G108 1541157 3,721,511,090
NASDAQ RXII US RXI Pharmaceuticals Corporation 74979C303 1533040
NASDAQ DMPI US DelMar Pharmaceuticals, Inc. 247078207 1498382 21,562,821
NASDAQ FLXN US Flexion Therapeutics, Inc. 33938J106 1419600 747,185,400
AMEX NBY US NovaBay Pharmaceuticals, Inc. 66987P102 1389545 52,867,800
NASDAQ CATB US Catabasis Pharmaceuticals, Inc 14875P107 1454789 33,844,761
NASDAQ CHMA US Chiasma, Inc. 16706W102 1339469 40,811,722
LSE AKR UK AKERS BIOSCIENCES INC 1321834 0
NASDAQ AKER US Akers Biosciences Inc. 00973E102 1321834
NASDAQ CLRBW US Cellectar Biosciences, Inc. Warrants expiring 8/20/2019 15117F120 1279704 6,196,648
NASDAQ CLRBZ US Cellectar Biosciences, Inc. Series A Warrants 15117F112 1279704 9,025,553
NASDAQ CLRB US Cellectar Biosciences, Inc. 15117F302 1279704 16,569,298
NASDAQ FENC US Fennec Pharmaceuticals Inc. 00686R200 1211583 144,178,400
OTC FENCF US Fennec Pharmaceuticals, Inc. 31447P100 1211583 67,682,000
NASDAQ CEMI US Chembio Diagnostics, Inc 163572209 1092662 103,413,223
NASDAQ ACER US Acer Therapeutics Inc. 68372T202 1069308 62,364,024
NASDAQ ACERW US Acer Therapeutics Inc. Warrant 00444P116 1069308 31,998
OTC ILIU US Interleukin Genetics, Inc. 458738101 1037649
OTC SNBPD US SUN BIOPHARMA INC 1029125
OTC SNBP US Sun BioPharma, Inc. 82935Y103 1029125
NYSE USNA US USANA Health Sciences, Inc. 90328M107 896264 1,874,835,000
NASDAQ STDY US SteadyMed Ltd. M84920103 1619087 93,184,852
NASDAQ DPRX US Dipexium Pharmaceuticals, Inc. 72942A107 1497504 11,316,480
NASDAQ HTBX US Heat Biologics, Inc. 42237K102 1476963 105,570,488
OTC BTHE US Boston Therapeutics Inc 101150100 1473579 2,416,846
AMEX XTNT US Xtant Medical Holdings, Inc. 98420P100 1453593 8,539,670
NASDAQ EVOK US Evoke Pharma, Inc. 30049G104 1403708 40,987,958
OTC AYTUZ US Aytu BioScience, Inc. Warrant 054754148 1385818 0
NASDAQ AYTU US Aytu BioScience, Inc. 054754106 1385818 8,598,831
NASDAQ ONTXW US Onconova Therapeutics, Inc. Warrants 68232V116 1130598 7,880,931
NASDAQ ONTX US Onconova Therapeutics, Inc. 68232V108 1130598 15,564,839
NASDAQ ITEK US Inotek Pharmaceuticals Corporation 45780V102 1281895 82,205,625
NASDAQ COLL US Collegium Pharmaceutical, Inc. 19459J104 1267565 695,328,615
OTC NWBOW US Northwest Biotherapeutics, Inc. Warrants 66737P113 1072379 64,741,780
OTC NWBO US Northwest Biotherapeutics, Inc. 66737P600 1072379
NASDAQ RIOT US Riot Blockchain Inc 92262A107 1167419 92,528,586
NASDAQ CBAY US Cymabay Therapeutics Inc. 23257D103 1042074 466,015,432
NASDAQ TTNP US Titan Pharmaceuticals, Inc. 888314309 910267 29,685,600
NASDAQ RPRX US Repros Therapeutics, Inc. 76028H209 897075
NASDAQ CTIC US CTI BioPharma Corp. 12648L106 891293 138,067,160
NASDAQ ARIA US ARIAD Pharmaceuticals, Inc. 04033A100 884731 4,635,467,750
NASDAQ MBOT US Microbot Medical Inc 59503A105 883975 37,142,502
NASDAQ CYTR US CytRx Corp. 232828509 799698 54,034,739
NASDAQ NAII US Natural Alternatives International, Inc. 638842302 787253 76,509,776
NASDAQ AVIR US Aviragen Therapeutics, Inc. 090694100 72444 23,576,035
NASDAQ BOTA US Biota Pharmaceuticals, Inc. 053761102 72444 0
AMEX BTX US BioTime, Inc. 09066L105 876343
AMEX BTX.WS US BioTime, Inc. Warrants exp. 2018-10-01 09066L162 876343 0
NASDAQ BSTC US BioSpecifics Technologies Corp. 090931106 875622 322,208,526
NASDAQ TECH US Bio-Techne Corp 09073M104 842023 5,366,175,600
NASDAQ EGRX US Eagle Pharmaceuticals, Inc. 269796108 827871 900,015,916
NASDAQ TLGT US Teligent, Inc. New 87960W104 352998 176,727,348
NASDAQ BLPH US Bellerophon Therapeutics, Inc. 078771102 1600132 84,325,493
NASDAQ RXDX US Ignyta, Inc. 451731103 1557421 1,516,153,100
NASDAQ TYME US Tyme Technologies, Inc. 90238J103 1537917 447,498,546
NASDAQ IMDZ US Immune Design Corp. 45252L103 1437786 96,077,929
OTC MSLP US MusclePharm Corp. 627335201 1415684 30,525,262
OTC COCP US Cocrystal Pharma, Inc. 19188J102 1412486
AMEX CRMD US CorMedix Inc. 21900C100 1410098 28,457,346
NASDAQ AQXP US Aquinox Pharmaceuticals, Inc. 03842B101 1404644 290,494,038
NASDAQ TKAI US Tokai Pharmaceuticals, Inc. 67011N105 1404281 4,235,265
NASDAQ CFRX US ContraFect Corporation 212326102 1478069 81,200,442
NASDAQ CFRXW US ContraFect Corporation 1478069 1,429,128
NASDAQ OCUL US Ocular Therapeutix, Inc. 67576A100 1393434 151,546,677
AMEX ATNM US Actinium Pharmaceuticals, Inc. 00507W107 1388320 54,407,252
NASDAQ CPRX US Catalyst Pharmaceuticals, Inc. 14888U101 1369568 306,968,648
NASDAQ FBIO US Fortress Biotech, Inc. 34960Q109 1429260 164,932,666
NASDAQ ASMB US Assembly Biosciences, Inc. 045396108 1426800 853,961,106
NASDAQ SUPN US Supernus Pharmaceuticals, Inc. 868459108 1356576 2,222,896,724
NASDAQ SGYPW US Synergy Pharmaceuticals, Inc., Warrants 871639118 1347613 13,497,296
NASDAQ SGYP US Synergy Pharmaceuticals, Inc. 871639308 1347613 519,645,914
NASDAQ CPXX US Celator Pharmaceuticals Inc. 15089R102 1327467 0
NASDAQ ANTH US Anthera Pharmaceuticals, Inc. 03674U201 1316175 20,471,522
OTC CHHE US China Health Industries Holdings, Inc. 1309057 17,695,729
NASDAQ ZGNX US Zogenix, Inc. 98978L105 1375151
NASDAQ ZFGN US Zafgen, Inc. 98885E103 1374690 161,328,438
NASDAQ SRRA US Sierra Oncology 74346L101 1290149
NASDAQ OMER US Omeros Corp. 682143102 1285819 787,382,831
NASDAQ ICPT US Intercept Pharmaceuticals, Inc. 45845P108 1270073 1,629,751,680
NASDAQ APEN US Apollo Endosurgery Inc. 548910306 1251769 93,665,326
NASDAQ LPTN US Lpath, Inc. 03767D108 1251769 45,361,885
NASDAQ CCXI US ChemoCentryx, Inc. 16383L106 1340652 467,551
NASDAQ TROVU US TrovaGene, Inc. 1213037 61,262,329
NASDAQ TROVW US TrovaGene, Inc. 1213037 11,304,358
NASDAQ TROV US TrovaGene, Inc. 897238309 1213037 11,049,099
NASDAQ ENTA US Enanta Pharmaceuticals, Inc. 29251M106 1177648 1,519,956,240
NASDAQ OHRP US Ohr Pharmaceutical, Inc. 67778H200 1173281 14,774,326
NASDAQ VTAE US Vitae Pharmaceuticals, Inc. 92847N103 1157602 605,420,613
NASDAQ GNMX US Aevi Genomic Medicine, Inc. 58436Q203 1138776
OTC MDGWW US Medgenics, Inc. 1138776 0
NASDAQ MDGN US Medgenics, Inc. 00835P105 1138776 206,702,940
NASDAQ BCLI US BrainStorm Cell Therapeutics Inc. 10501E201 1137883 68,561,589
NASDAQ BPTH US Bio-Path Holdings, Inc. 09057N102 1133818 24,413,908
NASDAQ GALTW US Galectin Therapeutics Inc Warrants 363225111 1133416 1,406,600
NASDAQ GALTU US Galectin Therapeutics Inc Units 363225301 1133416 144,176,500
NASDAQ GALT US Galectin Therapeutics Inc 363225202 1133416 189,891,000
NASDAQ BDSI US BioDelivery Sciences International, Inc. 09060J106 1103021 136,231,535
OTC IGXT US IntelGenx Technologies Corp. 45822R101 1098880 47,452,398
NASDAQ MDGL US Madrigal Pharmaceuticals, Inc. 87162T206 1157601
NASDAQ SNTA US Synta Pharmaceuticals, Inc. 558868105 1157601
NASDAQ FLML US Flamel Technologies S.A. 05337M104 1012477 429,512,210
NASDAQ AVDL US Avadel Pharmaceuticals plc 338488109 1012477 479,119,010
NASDAQ TGTX US TG Therapeutics, Inc. 88322Q108 1001316 803,727,231
NASDAQ MNKD US MannKind Corp. 56400P201 899460 292,121,370
NASDAQ BCRX US BioCryst Pharmaceuticals, Inc. 09058V103 882796 388,600,500
NASDAQ VICL US Vical Inc. 925602104 819050 16,384,940
OTC ENZN US Enzon Pharmaceuticals, Inc. 293904108 727510 11,053,750
NASDAQ EPZM US Epizyme, Inc. 29428V104 1571498 994,323,400
NASDAQ KPTI US Karyopharm Therapeutics Inc. 48576U106 1503802 578,893,273
NASDAQ OTIC US Otonomy, Inc. 68906L105 1493566 177,337,807
NASDAQ RTTR US Ritter Pharmaceuticals, Inc. 767836109 1460702 5,150,026
OTC RLMD US Relmada Therapeutics, Inc. 75955J105 1553643
TSXV KLH CA Stellar Biotechnologies 1540159
NASDAQ SBOT US Stellar Biotechnologies Inc. 85855A203 1540159 9,827,724
NASDAQ LPCN US Lipocine Inc. 53630X104 1535955 27,366,660
NASDAQ AGIO US Agios Pharmaceuticals, Inc. 00847X104 1439222 3,911,644,705
NASDAQ DRNA US Dicerna Pharmaceuticals, Inc. 253031108 1399529
OTC ILNS US Intellect Neurosciences, Inc. 45822W209 1337905 196,760
NASDAQ ALT US Altimmune, Inc. 02155H101 1326190 1,828,088
NASDAQ ARDX US Ardelyx, Inc. 039697107 1437402 363,101,972
NASDAQ IOVA US Iovance Biotherapeutics Inc. 53619R102 1425205
NASDAQ VTL US Vital Therapies, Inc. 92847R104 1280776 259,575,362
NASDAQ PRTO US Proteon Therapeutics, Inc. 74371L109 1359931 38,663,616
NASDAQ CUR US Neuralstem, Inc. 64127R302 1357459 27,617,990
OTC IPIX US Innovation Pharmaceuticals Inc 15115V101 1355250 0
NASDAQ ALDX US Aldeyra Therapeutics,Inc. 01438T106 1341235
NASDAQ SCYX US SCYNEXIS, Inc. 811292101 1178253 51,473,016
NASDAQ HALO US Halozyme Therapeutics, Inc. 40637H109 1159036 2,712,889,840
OTC OPLI US OphthaliX Inc. 24822L109 1218683 4,698,563
NASDAQ ARNA US Arena Pharmaceuticals, Inc. 040047102 1080709 1,429,820,760
AMEX PLX US Protalix BioTherapeutics, Inc. 74365A101 1006281 91,458,811
NASDAQ LJPC US La Jolla Pharmaceutical Co. 503459604 920465 807,783,750
NASDAQ OXGN US OXiGENE, Inc. 57667K109 908259
OTC MATN US Mateon Therapeutics, Inc. 691828404 908259
NASDAQ ONCE US Spark Therapeutics, Inc. 84652J103 1609351 1,983,214,608
NASDAQ SAGE US Sage Therapeutics, Inc. 78667J108 1597553
NASDAQ ADVM US Adverum Biotechnologies, Inc. 00773U108 1501756 303,667,000
NASDAQ GNCA US Genocea Biosciences, Inc. 372427104 1457612 26,946,040
NASDAQ TNXP US Tonix Pharmaceuticals Holding Corp. 890260201 1430306
AMEX AMPE US Ampio Pharmaceuticals, Inc. 03209T109 1411906 185,592,152
NASDAQ NSTG US NanoString Technologies, Inc. 63009R109 1401708 209,996,800
NYSE EBS US Emergent Biosolutions, Inc. 29089Q105 1367644 2,562,756,357
OTC LIXT US Lixte Biotechnology Holdings, Inc. 539319103 1335105 10,442,886
NASDAQ ECYT US Endocyte, Inc. 29269A102 1235007 152,212,544
AMEX RNN US Rexahn Pharmaceuticals, Inc, 761640101 1228627 65,171,834
NASDAQ DRRX US Durect Corp. 266605104 1082038 188,337,400
NASDAQ ACOR US Acorda Therapeutics, Inc. 00484M106 1008848 1,253,554,500
NASDAQ NBIX US Neurocrine Biosciences, Inc. 64125C109 914475 7,849,442,750
AMEX SYN US Synthetic Biologics, Inc. 87164U102 894158 69,271,024
NASDAQ GERN US Geron Corp. 374163103 886744 321,617,617
NASDAQ CLDX US Celldex Therapeutics, Inc. 15117B103 744218 368,177,600
NASDAQ FCSC US Fibrocell Science Inc. 315721209 357097 10,445,922
NASDAQ TXMD US TherapeuticsMD, Inc. 88338N107 25743 1,343,281,663
NASDAQ MRTX US Mirati Therapeutics, Inc. 60468T105 1576263 650,492,075
NASDAQ KIN US Kindred Biosciences, Inc. 494577109 1561743 242,490,000
NASDAQ EBIO US Eleven Biotherapeutics, Inc. 286221106 1485003 25,431,730
NASDAQ TRVN US Trevena, Inc. 89532E109 1429560
NASDAQ CNAT US Conatus Pharmaceuticals Inc. 20600T108 1383701 163,522,002
NASDAQ VNDA US Vanda Pharmaceuticals, Inc. 921659108 1347178 774,271,201
NASDAQ CARA US Cara Therapeutics, Inc. 140755109 1346830 492,458,320
NASDAQ XLRN US Acceleron Pharma Inc. 00434H108 1280600 1,730,703,170
NASDAQ CNCE US Concert Pharmaceuticals, Inc. 206022105 1367920 489,733,110
NASDAQ MEIP US MEI Pharma, Inc. 55279B202 1262104 82,311,450
NASDAQ CBIO US Catalyst Biosciences Inc. 14888D109 1124105 106,772,596
NASDAQ LXRX US Lexicon Pharmaceuticals, Inc. 528872302 1062822 1,157,178,720
NASDAQ PTX US Pernix Therapeutics Holdings, Inc. 71426V108 1024126 39,813,200
NASDAQ INSM US Insmed, Inc. 457669307 1104506 1,813,061,120
NASDAQ INVA US Innoviva, Inc. 88338T104 1080014 1,843,660,440
NASDAQ THRX US Theravance, Inc. 88338TAB0 1080014 0
LSE SHP UK SHIRE PLC 936402
NASDAQ SHPG US Shire Plc. 82481R106 936402 134,506,580,000
OTC SHPGF US Shire Plc. JE00B2QKY 936402 50,575,568,000
NASDAQ MYGN US Myriad Genetics, Inc. 62855J104 899923 2,887,104,000
NASDAQ IMGN US Immunogen, Inc. 45253H101 855654 778,418,370
NASDAQ LFVN US Lifevantage Corp. 53222K106 849146 68,147,200
NASDAQ JNP US Juniper Pharmaceuticals, Inc. 48203L107 821995 76,992,400
NASDAQ FLKS US Flex Pharma, Inc. 33938A105 1615219 75,804,046
NASDAQ OXFD US Oxford Immunotec Global PLC G6855A103 1586049 282,004,580
NASDAQ RELV US Reliv' International, Inc. 75952R100 768710 9,999,900
OTC PVCT US Provectus Biopharmaceuticals, Inc. 74373P108 315545 0
OTC PVCTW US Provectus Biopharmaceuticals, Inc. Warrant 2020-06-19 315545
OTC PCYN US Procyon Corp. 742806300 812306
OTC ULUR US ULURU Inc. 90403T209 1168220
NASDAQ VTVT US vTv Therapeutics Inc 918385105 1641489 71,342,349
OTC IDRAW US Idera Pharmaceuticals, Inc. 861838 0
NASDAQ IDRA US Idera Pharmaceuticals, Inc. 45168K306 861838 279,823,060
NASDAQ ATHX US Athersys, Inc. 04744L106 1368148 214,143,807
NASDAQ AMRN US Amarin Corp. Plc 023111206 897448 1,156,328,810
TSX QLT CA Qlt Inc 827809
NASDAQ NVLN US NOVELION THERAPEUTICS INC. 746927102 827809
NASDAQ QLTI US QLT, Inc. 6700K2029 827809
NASDAQ PULM US Pulmatrix, Inc. 74584P103 1574235 40,199,777
NASDAQ LOXO US Loxo Oncology, Inc. 548862101 1581720 3,105,513,704
NASDAQ ABUS US Arbutus Biopharma Corporation 87911B209 1447028 288,104,791
NASDAQ ESPR US Esperion Therapeutics, Inc. 29664W105 1434868 1,820,470,879
NASDAQ CBPO US China Biologic Products, Inc. 16938C106 1369868
NASDAQ GLYC US GlycoMimetics, Inc. 38000Q102 1253689 735,308,505
NASDAQ ALNY US Alnylam Pharmaceuticals, Inc. 02043Q107 1178670 12,340,764,920
NASDAQ INFI US Infinity Pharmaceuticals, Inc. 45665G303 1113148 105,828,881
NASDAQ CORT US Corcept Therapeutics, Inc. 218352102 1088856 3,153,840,100
NASDAQ MGNX US MacroGenics, Inc. 556099109 1125345 829,741,121
NASDAQ ARQL US ArQule, Inc. 04269E107 1019695 124,481
OTC SIGAQ US SIGA Technologies, Inc. 826917106 1010086 86,799,822
OTC SIGA US SIGA Technologies, Inc. 1010086 259,610,376
NASDAQ RGLS US Regulus Therapeutics Inc. 75915K101 1505512 120,696,540
NASDAQ OCRX US Ocera Therapeutics, Inc. 67552A108 1274644 47,454,805
NASDAQ SGNT US Sagent Pharmaceuticals, Inc. 786692103 1369786 714,946,560
NASDAQ AERI US Aerie Pharmaceuticals, Inc. 00771V108 1337553 2,053,125,654
NASDAQ FOLD US Amicus Therapeutics, Inc. 03152W109 1178879 2,604,908,824
NASDAQ ACHN US Achillion Pharmaceuticals, Inc. 00448Q201 1070336 390,145,000
OTC ACUR US Acura Pharmaceuticals, Inc. 00509L703 786947
NASDAQ MACK US Merrimack Pharmaceuticals, Inc. 590328100 1274792 146,633,280
NYSE CBM US Cambrex Corp. 132011107 820081 1,893,428
NASDAQ QDEL US QUIDEL Corp. 74838J101 353569 1,646,815,280
NASDAQ SGEN US Seattle Genetics, Inc. 812578102 1060736 8,303,653,440
NASDAQ ITCI US Intra-Cellular Therapies Inc. 46116X101 1567514 781,204,722
NASDAQ KERX US Keryx Biopharmaceuticals, Inc. 492515101 1114220 566,405,847
NASDAQ NUTR US Nutraceutical International Corp. 67060Y101 1050007
TYO 4875 JP Medicinova,inc. 1226616
NASDAQ MNOV US Medicinova, Inc. 58468P206 1226616 308,318,822
OTC SNYR US Synergy CHC Corp. 1562733 30,383,312
OTC SNNC US Sibannac, Inc. 1313938
OTC MIXX US MIX 1 LIFE, INC. 1501112 602,080
OTC ORGS US Orgenesis, Inc. 68619K105 1460602
OTC ENTB US Entest BioMedical Inc. 29383T300 1449447 2,052,096
OTC CYDY US CytoDyn Inc. 23283M101 1175680
NASDAQ ORMP US Oramed Pharmaceuticals, Inc. 68403P203 1176309
NASDAQ NEOG US Neogen Corp. 640491106 711377
OTC TBEV US High Performance Beverages Co 1504222 7,845
OTC LVYN US Lvyuan Green Building Material Technology Corp. 1580836
NASDAQ CSBR US Champions Oncology, Inc. 15870P307 771856
NASDAQ PPHMP US Peregrine Pharmaceuticals, 10.50% Ser E Cumulative Convertible Preferred Stock 713661403 704562
NASDAQ PPHM US Peregrine Pharmaceuticals, Inc. 713661304 704562
NASDAQ ONCS US OncoSec Medical Incorporated 68234L207 1444307
OTC PMCB US PharmaCyte Biotech, Inc. 71715X104 1157075
OTC VNTH US Nano Mobile Healthcare, Inc. 63010B101 1497130
OTC RCHA US Rich Pharmaceuticals, Inc. 76303T407 1504389
OTC NBIO US Nascent Biotech Inc. 63108Q101 1622057 6,733,843
OTC PKPH US Peak Pharmaceuticals, Inc. 70469W106 1452804 4,388,359
OTC CYIG US China YCT International Group, Inc. 847464 5,987,623
OTC ADYNF US Algae Dynamics Corp. 1607679
NASDAQ CJJD US China Jo-Jo Drugstores, Inc. 16949A206 1413263 39,082,751
NASDAQ VIVO US Meridian Bioscience, Inc. 589584101 794172 685,393,100
OTC ELTP US Elite Pharmaceuticals, Inc. 28659T200 1053369 110,431,141
NASDAQ ONVO US Organovo Holdings, Inc. 68620A104 1497253 146,690,825
OTC BZYR US Burzynski Research Institute, Inc. 724445
OTC GNBT US Generex Biotechnology Corp. 371485103 1059784 0
OTC NTRR US Neutra Corp. 1512886 1,363,298
OTC MINE US Minerco, Inc. 1451514 1,276,443,341
OTC PVOTF US Pivot Pharmaceuticals Inc. C124IO8Y0 1464165
NASDAQ DMTX US Dimension Therapeutics, Inc. 25433V105 1592288 149,109,487
NASDAQ ACRS US Aclaris Therapeutics, Inc. 00461U105 1557746 707,317,840
OTC AMBS US Amarantus Bioscience Holdings, Inc. 02300U205 1424812 1,551,120
OTC NPHC US Nutra Pharma Corp. 67060U109 1119643 10,008,394
OTC VGLS US VG Life Sciences Inc. 91822T101 1091326 854,507
OTC BGMD US BG Medicine, Inc. 08861T107 1407038 864,847
OTC VGEN US Vaccinogen, Inc. 918641101 1453001 3,768,221
OTC PXYN US Praxsyn Corporation 74006F105 1346973 9,800,000
NASDAQ HSKA US Heska Corp. 42805E306 1038133 632,379,960
OTC AUCL US Acucela Inc. 1400482 0
OTC CPMD US Cannapharmarx Inc. 13765D109 1081938 7,543,041
NASDAQ VBIV US VBI Vaccines, Inc. New 91790E102 704159 87,899,728
NASDAQ TBPH US Theravance Biopharma, Inc. G8807B106 1583107 1,524,666,780
OTC NRXGQ US NephroGenex, Inc. 1338095 100,055
NASDAQ NRX US NephroGenex, Inc. 640667101 1338095 1,400,763
OTC OVIT US OncoVista Innovative Therapies, Inc. 68232J105 1094847 230,545
NASDAQ ZSPH US ZS Pharma, Inc. 98979G105 1459266 0
NASDAQ VSTM US Verastem, Inc. 92337C104 1526119 127,942,000
NASDAQ BLCM US Bellicum Pharmaceuticals, Inc. 079481107 1358403 271,401,038
NASDAQ ALIM US Alimera Sciences, Inc. 016259103 1267602 82,117,027
NASDAQ PAHC US Phibro Animal Health Corporation 71742Q106 1069899 1,444,504,050
OTC TBUFF US Tribute Pharmaceuticals Canada Inc. 89609J106 1159019 0
NASDAQ OCAT US Ocata Therapeutics, Inc. 67457L100 1140098 357,566,268
NASDAQ CRIS US Curis, Inc. 231269101 1108205 104,025,079
NASDAQ NVAX US Novavax, Inc. 670002104 1000694 619,549
NASDAQ NKTR US Nektar Therapeutics 640268108 906709 12,853,518,230
NASDAQ EDGE US Edge Therapeutics, Inc. 279870109 1472091 401,391,207
NASDAQ NLNK US NewLink Genetics Corp 651511107 1126234 256,883,681
NASDAQ RGEN US Repligen Corp. 759916109 730272 1,570,149,144
NASDAQ OVAS US Ovascience Inc. 69014Q101 1544227 39,969,440
NASDAQ ALXA US Alexza Pharmaceuticals, Inc. 015384209 1344413 19,558,580
NASDAQ XNPT US XenoPort, Inc. 98411C100 1130591 0
NASDAQ CYTK US Cytokinetics, Inc. 23282W605 1061983 526,446,200
NASDAQ ACAD US ACADIA Pharmaceuticals, Inc. 004225108 1070494 3,935,410,920
NASDAQ IMMU US Immunomedics, Inc. 452907108 722830 2,208,353,595
NASDAQ SCMP US Sucampo Pharmaceuticals, Inc. 864909106 1365216 1,168,239,850
NASDAQ FATE US Fate Therapeutics, Inc. 31189P102 1434316 365,402,413
NASDAQ DARA US DARA Biosciences, Inc. 23703P304 919745 0
NASDAQ AXON US Axovant Sciences Ltd. G0750W104 1636050 232,402,195
NASDAQ PRTA US Prothena Corp plc G72800108 1559053 1,724,671,680
NASDAQ TSRO US TESARO, Inc. 881569107 1491576 3,755,104,430
NASDAQ ADXSW US Advaxis, Inc. Warrants 007624117 1100397
NASDAQ ADXS US Advaxis, Inc. 007624208 1100397
OTC TPIY US Tianyin Pharmaceutical Co., Inc. 1362718 0
AMEX TPI US Tianyin Pharmaceutical Co., Inc. 88630M104 1362718 4,709,247
OTC NRTI US Inergetics, Inc. 45671Q204 72170
NASDAQ VKTXW US Viking Therapeutics, Inc. Warrants exp. 2021-04-04 92686J114 1607678 114,823,697
NASDAQ VKTX US Viking Therapeutics, Inc. 92686J106 1607678 154,654,884
OTC INNV US Innovus Pharmaceuticals, Inc. 45778V106 1411879 16,077,999
NASDAQ VRML US Vermillion, Inc. 92407M206 926617
INSV US Insite Vision Inc 457660108 802724 0
NASDAQ JAGX US Jaguar Animal Health, Inc. 47008L106 1585608
AMEX PFNX US Pfenex Inc. 717071104 1478121 92,272,880
NASDAQ AMPH US Amphastar Pharmaceuticals, Inc. 03209R103 1297184 944,049,700
NASDAQ VCEL US Vericel Corporation 92346J108 887359 245,769,100
OTC EPRSQ US EPIRUS Biopharmaceuticals, Inc. 1135906 496,364
NASDAQ EPRS US EPIRUS Biopharmaceuticals, Inc. 29428P107 1135906 16,131,846
OTC CDXI US Cardax, Inc. 14141D102 1544238 20,620,508
NASDAQ RTRX US Retrophin, Inc. 761299106 1438533 957,075,169
OTC OSIR US Osiris Therapeutics, Inc. 68827R108 1360886 153,275,800
NASDAQ MBVX US MabVax Therapeutics Holdings, Inc. 55414P108 1109196 10,215,356
NASDAQ CYAN US Cyanotech Corp. 232437301 768408 23,661,100
NASDAQ TTPH US Tetraphase Pharmaceuticals, Inc. 88165N105 1373707 297,339,160
NASDAQ BIND US BIND Therapeutics, Inc. 233242106 1385228 10,652,269
OTC BINDQ US DNIB Unwind, Inc. 05548N107 1385228 2,924,152
NASDAQ RPTP US Raptor Pharmaceutical Corp. 75382F106 1070698 768,748,878
NASDAQ APRI US Apricus Biosciences, Inc. 03832V109 1017491 30,642,560
NASDAQ MRNS US Marinus Pharmaceuticals, Inc. 56854Q101 1267813 220,159,918
NASDAQ RIGL US Rigel Pharmaceuticals, Inc. 766559603 1034842 538,392,960
NASDAQ AGEN US Agenus Inc. 00847G705 1098972 373,596,005
OTC MCET US MultiCell Technologies, Inc. 811779 1,075,381
OTC PCNT US Point of Care Nano-Technology, Inc. 1504239 2,374,924
OTC ERBA US ERBA DIAGNOSTICS 1095858
AMEX ERB US ERBA Diagnostics, Inc. 29490B101 1095858 22,043,004
OTC MCTC US MicroChannel Technologies Corp. 1413488 86,183
OTC CRXM US Taxus Cardium Pharmaceuticals Group, Inc. 876767104 772320
NASDAQ LIFE US aTyr Pharma, Inc. 002120103 1339970 96,817,530
NASDAQ CLCD US CoLucid Pharmaceuticals, Inc. 19716T101 1348649 747,073,452
OTC WCUI US Wellness Center USA Inc 94973A103 1516887
NASDAQ AGLE US Aeglea BioTherapeutics, Inc. 00773J103 1636282 110,438,432
OTC GRMD US Green Meadow Prods Inc 1557340
NASDAQ CLSN US Celsion Corp. 15117N404 749647 21,022,657
AMEX NAVB US Navidea Biopharmaceuticals, Inc. 63937X103 810509
NASDAQ AKRX US Akorn, Inc. 009728106 3116 4,058,295,420
NASDAQ AIMT US Aimmune Therapeutics, Inc. 00900T107 1631650 1,873,505,540
NYSE PRGO US Perrigo Company plc G97822103 1585364
NASDAQ MCRB US Seres Therapeutics, Inc. 81750R102 1609809 446,244,420
NASDAQ SPHS US Sophiris Bio, Inc. 83578Q209 1563855 67,147,530
NASDAQ CERCW US Cerecor Inc. Class A Warrants 15671L117 1534120
NASDAQ CERCZ US Cerecor Inc. Class B Warrants 15671L125 1534120 428,154
NASDAQ CERC US Cerecor Inc. 15671L109 1534120 74,284,726
NASDAQ NEOS US Neos Therapeutics, Inc. 64052L106 1467652
OTC ISCO US International Stem Cell Corp. 460378102 1355790
NASDAQ AEGR US Aegerion Pharmaceuticals, Inc. 00767E102 1338042 58,164,250
NASDAQ NK US NantKwest, Inc. 63016Q102 1326110 388,464,490
OTC RSPI US RespireRx Pharmaceuticals Inc. 761227107 849636
NASDAQ EDIT US Editas Medicine, Inc. 28106W103 1650664 1,485,403,028
NASDAQ CORI US Corium International, Inc. 21887L107 1594337 391,584,336
NASDAQ KMPH US KemPharm, Inc. 488445107 1434647 84,280,222
NASDAQ ACHV US Achieve Life Sciences Inc 68230A106 949858
OTC ONXBW US OncoGenex Pharmaceuticals, Inc. Series B Warrants exp 2019-06-27 68230A122 949858
OTC ONXAW US OncoGenex Pharmaceuticals, Inc. Series A Warrants exp 2019-06-27 68230A114 949858
NASDAQ DSCO US Discovery Laboratories, Inc. 97382D105 946486 0
OTC WINT US Windtree Therapeutics, Inc. 254668403 946486
NSE PFIZER IN PFIZER LTD. 78003 0
BSE 500680 IN PFIZER LTD. 78003
LSE PFZ UK PFIZER INC 78003 0
NYSE PFE US Pfizer, Inc. 717081103 78003
NASDAQ BGNE US BeiGene, Ltd. 07725L102 1651308 74,427,923,306
NASDAQ VYGR US Voyager Therapeutics, Inc 92915B106 1640266 571,694,915
NASDAQ ADAP US Adaptimmune Therapeutics plc 00653A107 1621227
NASDAQ NVET US Nexvet Biopharma plc G6503X109 1618561 79,167,413
NASDAQ CDTX US Cidara Therapeutics, Inc. 171757107 1610618 123,108,740
NASDAQ MYOK US MyoKardia, Inc. 62857M105 1552451 1,793,617,834
NASDAQ SYBX US Synlogic, Inc. 60470J103 1527599 69,183,176
NASDAQ MIRN US Mirna Therapeutics, Inc. 87166L100 1527599 11,900,940
NASDAQ CDXC US ChromaDex Corporation 171077407 1386570 258,708,432
NASDAQ IMMY US Imprimis Pharmaceuticals, Inc. 45323A201 1360214 34,261,956
NASDAQ KALV US KalVista Pharmaceuticals, Inc. 141384107 1348911 118,546,962
NASDAQ CBYL US Carbylan Therapeutics, Inc. 483497103 1348911
OTC GBIM US GlobeImmune, Inc. 37957B100 1245104 1,552,925
NASDAQ ICCC US ImmuCell Corp. 452525306 811641
NASDAQ ABIO US ARCA biopharma, Inc. 00211Y209 907654 21,567,476
NASDAQ AXSM US Axsome Therapeutics, Inc. 05464T104 1579428 70,902,120
NASDAQ CYNA US Cynapsus Therapeutics Inc. 23257Y859 1532079
NASDAQ KURA US Kura Oncology, Inc. 50127T109 1422143 485,662,800
NASDAQ TCON US TRACON Pharmaceuticals, Inc. 89237H100 1394319 50,555,067
OTC PTEO US Proteo, Inc. 74369R100 1063104
NASDAQ SCLN US SciClone Pharmaceuticals, Inc. 80862K104 880771
AMEX CVM.WS US CEL-SCI Corp. Warrants 725363
AMEX CVMW US CEL-SCI Corp. Warrants 150837177 725363
AMEX CVM US CEL-SCI Corp. 150837508 725363
NYSE LCI US Lannett Co., Inc. 516012101 57725 875,351,219
NASDAQ ARLZ US Aralez Pharmaceuticals Inc. 03852X100 1660719 122,311,710
NASDAQ NATR US Nature's Sunshine Products, Inc. 639027101 275053 225,164,050
NYSE JNJ US Johnson & Johnson 478160104 200406
OTC WCRX US Warner Chilcott plc SB446CM73 1620602
NASDAQ BPMC US Blueprint Medicines Corporation 09627Y109 1597264 3,248,189,684
NASDAQ JUNO US Juno Therapeutics, Inc. 48205A109 1594864 9,052,203,440
NASDAQ EGLT US Egalet Corporation 28226B104 1586105 38,886,597
NASDAQ XENE US Xenon Pharmaceuticals Inc. 98420N105 1582313 60,333,430
NASDAQ ACT US Actavis G0083B108 1578845 8,967,815,000
NYSE AGN.PRA US Allergan plc 00BY9D6T8 1578845
NYSE AGN US Allergan plc G0177J108 1578845 62,341,155,000
NASDAQ DERM US Dermira, Inc. 24983L104 1557883 1,287,462,425
NASDAQ RARE US Ultragenyx Pharmaceutical Inc. 90400D108 1515673 2,414,086,085
NASDAQ CALA US Calithera Biosciences, Inc. 13089P101 1496671 294,442,500
NASDAQ IRWD US Ironwood Pharmaceuticals, Inc. 46333X108 1446847 2,433,893
NASDAQ ANAC US Anacor Pharmaceuticals, Inc. 032420101 1411158 4,450,804,472
NASDAQ PBYI US Puma Biotechnology Inc. 74587V107 1401667 2,556,601,937
NASDAQ RVNC US Revance Therapeutics, Inc. 761330109 1479290 1,014,053,710
OTC GALEW US Galena Biopharma, Inc. Warrants exp. 2018-09-18 363256124 1390478 0
OTC GALPW US Galena Biopharma, Inc. Warrants exp. 2017-12-21 363256116 1390478
NASDAQ GALE US Galena Biopharma, Inc. 363256108 1390478 10,205,109
NASDAQ ADMS US Adamas Pharmaceuticals, Inc. 00548A106 1328143 941,804,370
NASDAQ AVEO US AVEO Pharmaceuticals, Inc. 053588109 1325879 356,378,120
NASDAQ BIOD US Biodel, Inc. 01345P106 1322505
NASDAQ ALBO US Albireo Pharma, Inc. 09064M204 1322505
NASDAQ JAZZ US Jazz Pharmaceuticals, Inc. G50871105 1232524 9,571,114,440
NASDAQ MTEX US Mannatech, Inc. 563771203 1056358 40,107,000
NASDAQ IPXL US Impax Laboratories, Inc. 45256B101 1003642 1,496,031,514
NASDAQ OPK US Opko Health, Inc. 68375N103 944809 2,729,897,908
OTC LGNXZ US Ligand Pharmaceuticals Incorporated Glucagon Contingent Value 53220K181 886163
OTC LGNDZ US Ligand Pharmaceuticals Incorporated Roche Contingent Value 53220K215 886163 0
NASDAQ LGND US Ligand Pharmaceuticals Incorporated 53220K504 886163 3,905,738,471
OTC LGNYZ US Ligand Pharmaceuticals Incorporated General Contingent Value 53220K199 886163 0
OTC LGNZZ US Ligand Pharmaceuticals Incorporated Beta Contingent Value 53220K173 886163 247,288
NASDAQ FGEN US FibroGen, Inc. 31572Q808 921299 4,428,239,850
EPA MRK FR MERCK AND CO INC 310158
BSE 500126 IN MERCK LTD. 310158
NSE MERCK IN MERCK LTD. 310158 0
OTC MKGAF US Merck KGaA 589339100 310158 300,351,777,273
NYSE MRK US Merck & Co., Inc. 58933Y105 310158 169,183,080,000
OTC MKGAY US Merck KGaA 004741844 310158 101,553,485,454
NYSE BXLT US Baxalta Incorporated 07177M103 1620546 31,753,800,000
NASDAQ CHRS US Coherus BioSciences, Inc. 19249H103 1512762 654,257,551
NASDAQ KITE US Kite Pharma, Inc. 49803L109 1510580
NASDAQ HZNP US Horizon Pharma plc G4617B105 1492426 2,549,776,445
NASDAQ CLVS US Clovis Oncology, Inc. 189464100 1466301 3,020,624,750
NASDAQ OPHT US Ophthotech Corp 683745103 1410939 109,943,350
NASDAQ CBMG US Cellular Biomedicine Group, Inc. 15117P102 1378624 298,471,035
NASDAQ TBRA US Tobira Therapeutics, Inc. 88883P101 1311596 791,952,350
NASDAQ AGTC US Applied Genetic Technologies Corp 03820J100 1273636 85,013,600
NASDAQ STML US Stemline Therapeutics, Inc. 85858C107 1264587 389,510,783
NASDAQ AGRX US Agile Therapeutics, Inc. 00847L100 1261249 108,268,559
OTC PSTIW US Pluristem Therapeutics, Inc. Warrants exp. 2017 72940R128 1158780
NASDAQ PSTI US Pluristem Therapeutics, Inc. 72940R102 1158780
NASDAQ CMRX US Chimerix, Inc. 16934W106 1117480 218,855,765
NASDAQ MDCO US Medicines Company 584688105 1113481 2,428,809,600
NASDAQ DVAX US Dynavax Technologies Corp. 268158201 1029142 997,345,000
NASDAQ SNSS US Sunesis Pharmaceuticals, Inc. 867328601 1061027 109,155,580
NASDAQ GILD US Gilead Sciences, Inc. 375558103 882095 112,721,740,000
NASDAQ SPPI US Spectrum Pharmaceuticals, Inc. 84763A108 831547 1,925,494,940
NASDAQ ATRA US Atara Biotherapeutics, Inc. 046513107 1604464 1,135,156,500
TSX ENL CA Endo International Plc 1593034
NASDAQ ENDP US Endo International plc G30401106 1593034 1,594,354,860
NYSE ZTS US Zoetis Inc. 98978V103 1555280
EPA ABBV FR AbbVie Inc. 1551152 0
NYSE ABBV US AbbVie Inc. 00287Y109 1551152 197,505,630,000
NASDAQ PETX US Aratana Therapeutics, Inc. 03874P101 1509190 205,012,021
NASDAQ CTMX US CytomX Therapeutics, Inc. 23284F105 1501989 950,649,629
NASDAQ MNTA US Momenta Pharmaceuticals, Inc. 60877T100 1235010 1,227,350,950
NASDAQ PTLA US Portola Pharmaceuticals, Inc. 737010108 1269021 3,196,357,632
NASDAQ FPRX US Five Prime Therapeutics, Inc. 33830X104 1175505 620,082,600
OTC MSTVW US Mast Therapeutics, Inc. Warrants exp. 2019-11-12 576314132 1160308
OTC MTPSW US Mast Therapeutics, Inc. Warrants exp. 2016-11-16 576314116 1160308
OTC MSTPW US Mast Therapeutics, Inc. Warrants exp. 2018-06-18 576314124 1160308
OTC MSTTW US Mast Therapeutics, Inc. Warrants exp. 2019-11-12 576314140 1160308
NASDAQ SVRA US Savara Inc 576314108 1160308 287,366,967
NASDAQ DEPO US DepoMed, Inc. 249908104 1005201 492,010,350
NASDAQ IONS US Ionis Pharmaceuticals, Inc. 464330109 874015 6,585,391,500
NASDAQ SRPT US Sarepta Therapeutics, Inc. 803607100 873303 4,158,062,240
NASDAQ REGN US Regeneron Pharmaceuticals, Inc. 75886F107 872589 43,810,602,080
NASDAQ AMAG US AMAG Pharmaceuticals, Inc. 00163U106 792977 510,243,950
NASDAQ PGNX US Progenics Pharmaceuticals, Inc. 743187106 835887 460,268,500
NASDAQ HRTX US Heron Therapeutics, Inc. 427746102 818033 1,316,476,800
NASDAQ CRVS US Corvus Pharmaceuticals, Inc. 221015100 1626971 202,348,640
NASDAQ RGNX US REGENXBIO Inc. 75901B107 1590877 906,542,000
NASDAQ AKBA US Akebia Therapeutics, Inc. 00972D105 1517022 714,875,152
NASDAQ INSY US Insys Therapeutics Inc. 45824V209 1516479
NASDAQ OREX US Orexigen Therapeutics, Inc. 686164104 1382911
NASDAQ RDUS US Radius Health, Inc. 750469207 1428522 1,704,538,732
NASDAQ OMED US OncoMed Pharmaceuticals, Inc. 68234X102 1302573 107,339,174
NASDAQ AKAO US Achaogen, Inc. 004449104 1301501 467,111,548
NASDAQ MTEM US Molecular Templates, Inc. 885807206 1183765 205,247,948
NASDAQ THLD US Threshold Pharmaceuticals, Inc. 608550109 1183765 9,679,816
NASDAQ ANIP US ANI Pharmaceuticals, Inc. 00182C103 1023024 797,772,640
NASDAQ MDVN US Medivation, Inc. 58501N101 1011835 13,431,573,770
NASDAQ PTCT US PTC Therapeutics, Inc. 69366J200 1070081 1,018,377,608
NASDAQ PTIE US Pain Therapeutics, Inc. 69562K100 1069530 47,662,020
NASDAQ SGMO US Sangamo BioSciences, Inc. 800677106 1001233 1,750,375,000
NASDAQ PDLI US PDL BioPharma, Inc. 69329Y104 882104 0
LSE ABT UK ABBOTT LABORATORIES 1800 0
NYSE ABT US Abbott Laboratories 002824100 1800 111,248,573,520
NYSE CTLT US Catalent Inc. 148806102 1596783 6,051,874,915
NASDAQ VSAR US Versartis, Inc.. 92529L102 1513818 74,928,000
NASDAQ RLYP US Relypsa, Inc. 759531106 1416792 1,432,136,254
OTC TLOG US TetraLogic Pharmaceuticals Corporation 88165U109 1361248 1,065,071
NASDAQ BLUE US bluebird bio, Inc. 09609G100 1293971
NASDAQ ARRY US Array BioPharma, Inc. 04269X105 1100412 2,514,969,080
NASDAQ VVUS US VIVUS, Inc. 928551100 881524 48,679,960
NASDAQ VRTX US Vertex Pharmaceuticals Inc. 92532F100 875320 42,347,848,280
NASDAQ CELG US Celgene Corp. 151020104 816284 85,734,584,000
NASDAQ CELGZ US Celgene Corporation Series A Contingent Value Rights 151020112 816284 774,440,000
NASDAQ ALPN US Alpine Immune Sciences Inc 02083G100 1626199 129,540,368
NASDAQ NVLS US Nivalis Therapeutics, Inc. 65481J109 1626199 27,808,308
NASDAQ MYL US Mylan N.V. N59465109 1623613 24,809,400,000
NASDAQ NERV US Minerva Neurosciences, Inc. 603380106 1598646 269,810,369
NYSE MNK US Maillinckrodt plc. G5785G107 1567892
NASDAQ LNTH US Lantheus Holdings, Inc. 516544103 1521036 923,255,600
NASDAQ AMGN US Amgen Inc. 031162100 318154 143,675,330,000
OTC ENZB US EnzymeBioSystems 29414C201 1471968 24,091
OTC ENZBD US ENZYMEBIOSYSTEMS 1471968
NASDAQ ADRO US Aduro Biotech, Inc. 00739L101 1435049 503,621,138
NASDAQ ACRX US AcelRx Pharmaceuticals, Inc. 00444T100 1427925 95,049,144
NASDAQ XNCR US Xencor, Inc. 98401F105 1326732 1,096,273,073
NASDAQ CEMP US Cempra, Inc. 58549G100 1461993
NASDAQ DARE US Dare Bioscience Inc 15708Q105 1401914 12,460,318
NASDAQ PCRX US Pacira Pharmaceuticals, Inc. 695127100 1396814 1,626,612,600
NASDAQ PRTK US Paratek Pharmaceuticals, Inc. 699374302 1178711 429,142,568
NASDAQ BMRN US BioMarin Pharmaceutical, Inc. 09061G101 1048477 16,039,434,800
NASDAQ ALXN US Alexion Pharmaceuticals, Inc. 015351109 899866 28,820,250,000
NASDAQ IDXX US IDEXX Laboratories, Inc. 45168D104 874716 16,693,549,680
EPA LLY FR Eli Lilly & Co. 59478
NYSE LLY US Eli Lilly & Co. 532457108 59478 91,956,480,000
OTC RGBP US Regen Biopharma, Inc. 75886M102 1589150
OTC RGBPP US Regen Biopharma, Inc. Preferred 75886M201 1589150
OTC DDXS US Diadexus, Inc. 922390208 1036968 0
OTC DDXSQ US Diadexus, Inc. 1036968 82,001
NASDAQ ALKS US Alkermes plc G01767105 1520262 9,102,703,320
NYSE BMY US Bristol-Myers Squibb Co. 110122108 14272 105,691,250,000
OTC BMYMP US Bristol-Myers Squibb Co. 110122908 14272 1,648,240,650,000
NASDAQ ALDR US Alder BioPharmaceuticals, Inc. 014339105 1423824 1,077,592,867
NASDAQ UTHR US United Therapeutics Corp. 91307C102 1082554 6,040,377,000
NASDAQ BIIB US Biogen Inc. 09062X103 875045 77,923,338,000
BLUD US Immucor Inc 452526106 736822
OTC MDRM US Modern Mobility Aids, Inc. 1497165 3,210,754
OTC VODG US Vitro Diagnostics, Inc. 928501303 793171 1,202,978
OTC SUWN US Sunwin Stevia International, Inc. 86803D109 806592
NASDAQ VTGN US VistaGen Therapeutics, Inc. 92840H202 1411685 15,728,305
OTC KBPHD US Kyto Biopharma, Inc. 501572200 1164888
OTC KBPH US Kyto Biopharma, Inc. 501572101 1164888
NASDAQ QTNT US Quotient Limited G73268107 1596946
NYSE PBH US Prestige Brands Holdings, Inc. 74112D101 1295947 2,402,294,930
OTC TRGM US Targeted Medical Pharma, Inc. 876140104 1420030 544,361
NASDAQ POZN US Pozen, Inc. 73941U102 1059790 0
NYSE ALR US Alere Inc. 01449J105 1145460 4,454,486,400
NYSE ALR.PRB US Alere Inc. 1145460
OTC GOGC US Global Green Inc. 1522724 14,915,229
NYSE VRX US Valeant Pharmaceuticals International, Inc. 91911K102 885590 6,806,436,000
OTC IAGX US Imagenetix, Inc. 45247F104 839441 142,060
OTC HGEN US Humanigen, Inc. 48344T100 1293310 0
OTC KBIO US KaloBios Pharmaceuticals, Inc. 444863104 1293310 41,947,769
NASDAQ RCPT US Receptos, Inc. 756207106 1463729
NYSE HSP US Hospira 441060100 1274057 0
NASDAQ NTLA US Intellia Therapeutics, Inc. 45826J105 1652130 869,520,190
OTC TAUG US Tauriga Sciences, Inc. 1142790
OTC PLPL US Plandai Biotechnology, Inc. 72703D100 1317880 3,513,266
OTC RGDXQ US Response Genetics, Inc. 76123U105 1124608
RGDX US 1124608
HPTX US Hyperion Therapeutics Inc 44915N101 1386858
ICEL US Cellular Dynamics International, Inc. 15117V109 1482080
GEVA US Synageva Biopharma Corp 87159A103 911326
ASPX US Auspex Pharmaceuticals, Inc. 05211J102 1454189 0
OTC ILIM US IL2M International Corp. 1520512 57,255
NASDAQ SLXP US Salix Therapeuticals, Inc. 795435106 1009356 10,981,902,690
OTC OMBP US Omni Bio Pharmaceutical, Inc. 68216L100 1389870 784,332
OTC ATOA US Altovida Inc. 1529293 6,365,407
NASDAQ AVNR US Avanir Pharmaceuticals Inc 05348P401 858803 2,735,122,596
OTC BOPH US Bohai Pharmaceuticals Group Inc. 097316103 1443242 8,180,306
OTC SVFC US Intellicell Biosciences, Inc. 45825A105 1125280 300,169
OTC CCYG US CellCyte Genetics Corp. 1325279 148,193
OTC AHROQ US Atheronova, Inc. 1377053
OTC PMBS US PuraMed BioScience, Inc. 746094200 1409565 10,395
OTC DRNK US NoHo, Inc. 1535469
OTC CYDI US Cybrdi, Inc. 19002 961,803
OTC SKBI US Skystar Bio-Pharmaceutical Company 830884300 1076939 428,723
OTC TNGNQ US Tengion, Inc. 88034G208 1296391 88,098
OTC HBMK US Hubei Minkang Pharmaceutical Ltd 44352W101 1375850 52,189,045
OTC MLPH US Molecular Pharmacology (USA), Ltd. 60852T109 1191357 223,107
NASDAQ DRTX US Durata Therapeutics Inc 26658A107 1544116 647,012,000
OTC GFOO US Genufood Energy Enzymes Corp. 1510518 160,003
OTC HRDN US DC Brands International, Inc. 1393463 33,886
OTC ALSE US Alseres Pharmaceuticals, Inc. 021152202 94784 1,531,786,000
NASDAQ AMBI US Ambit Biosciences Corp 02318X100 1131543 266,440,083
ITMN US 45884X103 1087432
NASDAQ IDIX US Idenix Pharmaceuticals Inc 45166R204 1093649 3,698,716,000
OTC AFFY US Affymax, Inc. 00826A109 1158223 1,874,500
OTC CPDU US China Pediatric Pharmaceuticals, Inc. 16948X108 1354071 891,122
CHTP US Chelsea Therapeutics International, Ltd. 163428105 1333763
OTC CHRI US China Health Resource, Inc. 1173784 369,828
NASDAQ HITK US Hi-Tech Pharmacal Co. 42840B101 887497 618,427,800
OTC ANDN US Andain, Inc. 1321502 0
OTC TGLP US Tongli Pharmaceuticals (USA), Inc. 89025Q106 1052284 736,406
SVNTQ US Savient Pharmaceuticals Inc 80517Q100 722104
NASDAQ CRTX US Chiesi USA Inc 21924P103 1145404 298,893,548
NASDAQ SNTS US Santarus, Inc 802817304 1172480 1,945,014,869,000
OTC AOBI US American Oriental Bioengineering, Inc. 028731404 1090514 182,697,955
AOB US 1090514
PBTH US Prolor Biotech, Inc. 74344F106 1268659
OTC MYRX US Myrexis, Inc. 62856H107 1459450 2,361
OTC SGTI US Shengtai Pharmaceutical, Inc. 823214200 1295079 287,547
OTC GFRP US GFR Pharmaceuticals, Inc. 36169W100 1096294 4,207,994
OTC UGNEQ US Unigene Laboratories, Inc. 904753100 352747
OTC PARS US Pharmos Corp. 717139307 713275 1,197,749
OTC CELZ US Creative Medical Technology Holdings, Inc. 1187953 0
OTC JLLM US Jolley Marketing, Inc. 1187953