Activist Investor 13D, 13G Filings - Manager: Samuel Isaly


This page shows a list of all the recent 13D/G filings made by Orbimed Advisors Llc. Schedule 13D is commonly referred to as a “beneficial ownership report.” The term "beneficial owner" is defined under SEC rules. It includes any person who directly or indirectly shares voting power or investment power (the power to sell the security).

When a person or group of persons acquires beneficial ownership of more than 5% of a voting class of a company’s equity securities, they are required to file a Schedule 13D within ten days after the purchase. Click the link icon to see the full transaction history.

DateForm Target Prev
Shares
Current
Shares
Change
(Percent)
Ownership
(Percent)
Change
(Percent)
2018‑09‑19 SC 13D/A XTNT / Xtant Medical Holdings, Inc. 9,214,321 10,414,321 13.02 72.6 3.12
2018‑09‑07 SC 13D/A STDY / SteadyMed Ltd. 3,952,696 0 -100.00 0.0 -100.00
2018‑08‑31 SC 13D/A VRAY / ViewRay, Inc. 7,711,409 6,515,891 -15.50 6.91 -15.53
2018‑08‑21 SC 13D/A VRAY / ViewRay, Inc. 8,418,964 7,711,409 -8.40 8.18 -26.50
2018‑08‑15 SC 13D RLM / Realm Therapeutics plc 35,751,953 28.2
2018‑08‑13 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 8,418,964 -14.67 11.13 -15.23
2018‑08‑10 SC 13D/A RYTM / Rhythm Pharmaceuticals, Inc. 2,065,000 1,629,700 -21.08 4.76 -21.97
2018‑08‑02 SC 13D/A NBRV / Nabriva Therapeutics AG 3,919,600 4,644,600 18.50 6.99 -52.12
2018‑07‑30 SC 13G CRNX / Crinetics Pharmaceuticals, Inc. 1,914,282 8.01
2018‑07‑11 SC 13D TCDA / Tricida, Inc. 10,889,280 25.96
2018‑07‑02 SC 13D/A ARPO / Aerpio Pharmaceuticals Inc 5,193,946 13.37
2018‑06‑27 SC 13D/A RYTM / Rhythm Pharmaceuticals, Inc. 2,375,000 2,065,000 -13.05 6.1 -29.32
2018‑06‑22 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 3,950,000 3,140,000 -20.51 5.82 -20.49
2018‑06‑15 SC 13D/A ASND / Ascendis Pharma AS 4,374,391 3,763,291 -13.97 9.05 -23.31
2018‑06‑04 SC 13D/A RYTM / Rhythm Pharmaceuticals, Inc. 2,901,295 2,375,000 -18.14 8.63 -18.81
2018‑05‑29 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 4,550,000 3,950,000 -13.19 7.32 -13.37
2018‑05‑02 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 5,550,000 4,550,000 -18.02 8.45 -22.33
2018‑05‑01 SC 13D/A STDY / SteadyMed Ltd. 3,952,696 3,952,696 0.00 13.9 0.00
2018‑04‑12 SC 13D/A MIRN / Mirna Therapeutics, Inc. 2,029,996 2,029,996 0.00 7.98 -15.82
2018‑03‑29 SC 13D/A ADAP / Adaptimmune Therapeutics plc 36,896,260 30,607,860 -17.04 5.44 -17.07
2018‑03‑14 SC 13D/A CRVS / Corvus Pharmaceuticals, Inc. 5,379,349 5,967,584 10.94 20.47 -19.95
2018‑03‑06 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 9,866,102 0.00 13.13 -9.57
2018‑02‑21 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 5,550,000 5,550,000 0.00 10.88 -12.19
2018‑02‑16 SC 13D/A NTLA / Intellia Therapeutics, Inc. 2,537,684 2,113,000 -16.74 4.99 -16.69
2018‑02‑15 SC 13D/A XTNT / Xtant Medical Holdings, Inc. 2,838,903 9,214,321 224.57 70.4 409.41
2018‑02‑13 SC 13G/A IMGN / Immunogen, Inc. 8,834,147 1,515,572 -82.84 1.15 -88.32
2018‑02‑13 SC 13G/A INFI / Infinity Pharmaceuticals, Inc. 3,250,300 0 -100.00 0.0 -100.00
2018‑02‑13 SC 13G/A INSM / Insmed, Inc. 5,301,805 859,700 -83.78 1.12 -86.93
2018‑02‑13 SC 13G/A IMMU / Immunomedics, Inc. 9,677,008 5,019,776 -48.13 3.3 -61.85
2018‑02‑13 SC 13G/A INSY / Insys Therapeutics Inc. 6,071,440 2,914,000 -52.00 3.97 -53.07
2018‑02‑13 SC 13G/A IOVA / Iovance Biotherapeutics Inc. 5,656,626 3,246,226 -42.61 4.47 -49.03
2018‑02‑13 SC 13G/A ITEK / Inotek Pharmaceuticals Corporation 2,788,111 474,052 -83.00 1.71 -82.95
2018‑02‑13 SC 13G/A NLNK / NewLink Genetics Corp 1,991,700 0 -100.00 0.0 -100.00
2018‑02‑13 SC 13G/A OBSV / Obseva SA 2,559,931 2,605,531 1.78 7.02 -18.75
2018‑02‑13 SC 13G/A PBYI / Puma Biotechnology Inc. 2,275,825 1,238,846 -45.56 3.3 -46.60
2018‑02‑13 SC 13G/A PRQR / ProQR Therapeutics N.V. 2,305,446 662,287 -71.27 2.08 -78.95
2018‑02‑13 SC 13G/A SGYP / Synergy Pharmaceuticals, Inc. 18,241,398 0 -100.00 0.0 -100.00
2018‑02‑13 SC 13G SRRA / Sierra Oncology 0 3,203,704 6.13
2018‑02‑13 SC 13G/A WMGIZ / Wright Medical Group N.V. 7,584,334 4,074,064 -46.28 3.86 -47.41
2018‑02‑13 SC 13G/A XENE / Xenon Pharmaceuticals Inc. 634,812 3.55
2018‑02‑13 SC 13G/A ACHN / Achillion Pharmaceuticals, Inc. 13,107,200 4,936,173 -62.34 3.58 -62.67
2018‑02‑13 SC 13G/A AGLE / Aeglea BioTherapeutics, Inc. 1,360,224 1,469,524 8.04 8.83 -12.92
2018‑02‑13 SC 13G/A ARRY / Array BioPharma, Inc. 16,088,800 4,299,200 -73.28 2.18 -77.17
2018‑02‑13 SC 13G/A ASMB / Assembly Biosciences, Inc. 1,397,100 625,300 -55.24 3.11 -61.65
2018‑02‑13 SC 13G/A BOLD / Audentes Therapeutics, Inc. 4,129,638 13.83
2018‑02‑13 SC 13G/A CLLS / Cellectis S.A. 1,826,500 645,000 -64.69 1.8 -65.18
2018‑02‑13 SC 13G/A EHTH / eHealth, Inc. 1,820,000 991,500 -45.52 5.32 -46.37
2018‑02‑13 SC 13G/A FLDM / Fluidigm Corp. 2,056,861 1,467,120 -28.67 3.79 -46.01
2018‑02‑13 SC 13G/A GKOS / Glaukos Corp. 2,180,000 836,500 -61.63 2.42 -62.77
2018‑02‑07 SC 13D/A RYTM / Rhythm Pharmaceuticals, Inc. 2,901,295 10.63
2018‑01‑29 SC 13D/A ASND / Ascendis Pharma AS 4,568,291 4,374,391 -4.24 11.8 -16.31
2018‑01‑29 SC 13D/A NTLA / Intellia Therapeutics, Inc. 2,537,684 2,537,684 0.00 5.99 0.00
2018‑01‑26 SC 13D/A MIRN / Mirna Therapeutics, Inc. 1,314,996 2,029,996 54.37 9.48 17.33
2018‑01‑26 SC 13D/A VRNA / Verona Pharma plc 11,871,112 11.12
2018‑01‑26 SC 13D/A ROKA / Roka Bioscience, Inc. 571,428 571,428 0.00 10.24 0.00
2018‑01‑26 SC 13D/A STDY / SteadyMed Ltd. 3,952,696 3,952,696 0.00 13.9 -4.79
2018‑01‑26 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 9,866,102 0.00 14.52 -0.14
2018‑01‑26 SC 13D/A SELB / Selecta Biosciences, Inc. 1,849,371 1,849,371 0.00 8.28 -1.19
2018‑01‑26 SC 13D/A ADAP / Adaptimmune Therapeutics plc 28,041,004 36,896,260 31.58 6.56 -0.61
2018‑01‑26 SC 13D/A CRVS / Corvus Pharmaceuticals, Inc. 5,258,450 5,379,349 2.30 25.57 -0.78
2018‑01‑26 SC 13D/A ASNS / Arsanis, Inc. 1,868,966 1,868,966 0.00 13.07 0.00
2018‑01‑26 SC 13D/A CMTA / Clementia Pharmaceuticals Inc. 10,425,225 32.87
2018‑01‑26 SC 13D/A ALPN / Alpine Immune Sciences Inc 3,298,516 23.76
2018‑01‑26 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 5,550,000 5,550,000 0.00 12.39 0.00
2018‑01‑26 SC 13D/A NBRV / Nabriva Therapeutics AG 307,179 3,919,600 1,176.00 14.6 0.55
2018‑01‑17 SC 13D/A XTNT / Xtant Medical Holdings, Inc. 1,952,670 2,838,903 45.39 13.82 39.60
2018‑01‑12 SC 13G KALA / Kala Pharmaceuticals, Inc. 2,692,715 10.98
2018‑01‑05 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 7,259,620 5,550,000 -23.55 12.39 -26.69
2017‑11‑30 SC 13D ASNS / Arsanis, Inc. 1,868,966 13.07
2017‑11‑20 SC 13D/A LOXO / Loxo Oncology, Inc. 1,728,000 1,458,000 -15.62 4.87 -27.96
2017‑11‑08 SC 13D/A NTLA / Intellia Therapeutics, Inc. 2,662,180 2,537,684 -4.68 5.99 -19.05
2017‑10‑27 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 9,866,102 0.00 14.54 -12.41
2017‑10‑05 SC 13D/A ROKA / Roka Bioscience, Inc. 773,045 571,428 -26.08 10.24 -26.12
2017‑10‑02 SC 13D/A ROKA / Roka Bioscience, Inc. 1,247,721 773,045 -38.04 13.86 -38.01
2017‑09‑28 SC 13D/A ROKA / Roka Bioscience, Inc. 1,389,622 1,247,721 -10.21 22.36 -10.24
2017‑09‑07 SC 13D MIRN / Mirna Therapeutics, Inc. 1,314,996 8.08
2017‑08‑23 SC 13D/A ROKA / Roka Bioscience, Inc. 1,464,898 1,389,622 -5.14 24.91 -5.29
2017‑08‑15 SC 13D/A SELB / Selecta Biosciences, Inc. 1,842,797 1,849,371 0.36 8.38 -18.64
2017‑08‑09 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 9,866,102 0.00 16.6 -6.21
2017‑08‑03 SC 13D NVLS / Nivalis Therapeutics, Inc. 3,298,516 23.76
2017‑07‑06 SC 13D/A OTIC / Otonomy, Inc. 1,850,094 1,397,567 -24.46 4.62 -24.88
2017‑06‑21 SC 13D/A ASND / Ascendis Pharma AS 4,198,291 4,568,291 8.81 14.1 6.02
2017‑06‑15 SC 13G CTIC / CTI BioPharma Corp. 5,000,000 11.6
2017‑05‑30 SC 13D XTNT / Xtant Medical Holdings, Inc. 1,862,030 1,952,670 4.87 9.9 -0.90
2017‑05‑08 SC 13D VNAPF / Verona Pharma Plc 11,871,112 11.8
2017‑04‑28 SC 13D/A STDY / SteadyMed Ltd. 3,072,196 3,952,696 28.66 14.6 2.82
2017‑03‑21 SC 13D/A VRAY / ViewRay, Inc. 9,866,102 9,866,102 0.00 17.7 -5.85
2017‑03‑06 SC 13D/A AFMD / Affimed N.V. 3,055,000 2,020,000 -33.88 4.67 -33.85
2017‑02‑13 SC 13G/A SRRA / Sierra Oncology 1,989,949 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A XTNT / Xtant Medical Holdings, Inc. 1,267,076 1,862,030 46.95 9.99 0.00
2017‑02‑13 SC 13G NLNK / NewLink Genetics Corp 1,991,700 6.84
2017‑02‑13 SC 13G/A SGYP / Synergy Pharmaceuticals, Inc. 15,138,384 18,241,398 20.50 9.1 -23.91
2017‑02‑13 SC 13G/A SIEN / Sientra, Inc. 1,357,500 742,574 -45.30 3.99 -47.08
2017‑02‑13 SC 13G/A XNPT / XenoPort, Inc. 5,768,400 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A IMGN / Immunogen, Inc. 6,095,647 8,834,147 44.93 9.85 40.51
2017‑02‑13 SC 13G/A IMMU / Immunomedics, Inc. 9,677,008 9,677,008 0.00 8.65 -10.18
2017‑02‑13 SC 13G ITEK / Inotek Pharmaceuticals Corporation 2,788,111 10.03
2017‑02‑13 SC 13G IOVA / Iovance Biotherapeutics Inc. 5,656,626 8.77
2017‑02‑13 SC 13G CLLS / Cellectis S.A. 1,826,500 5.17
2017‑02‑13 SC 13G/A FLDM / Fluidigm Corp. 2,628,650 2,056,861 -21.75 7.02 -22.60
2017‑02‑13 SC 13G/A GKOS / Glaukos Corp. 2,897,937 2,180,000 -24.77 6.5 -28.02
2017‑02‑13 SC 13G/A PRQR / ProQR Therapeutics N.V. 2,271,500 2,305,446 1.49 9.88 1.54
2017‑02‑13 SC 13G/A WMGIZ / Wright Medical Group N.V. 8,245,111 7,584,334 -8.01 7.34 -8.59
2017‑02‑13 SC 13G/A IRWD / Ironwood Pharmaceuticals, Inc. 11,226,400 7,241,300 -35.50 4.95 -44.00
2017‑02‑13 SC 13G/A MGLN / Magellan Health, Inc. 1,833,000 801,600 -56.27 3.45 -51.88
2017‑02‑13 SC 13G/A OPHT / Ophthotech Corp 2,011,500 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A PBYI / Puma Biotechnology Inc. 2,238,825 2,275,825 1.65 6.18 -10.43
2017‑02‑13 SC 13G/A EHTH / eHealth, Inc. 1,300,000 1,820,000 40.00 9.92 38.16
2017‑02‑13 SC 13G/A INFI / Infinity Pharmaceuticals, Inc. 4,416,300 3,250,300 -26.40 6.54 -27.09
2017‑02‑13 SC 13G/A INSM / Insmed, Inc. 3,469,900 5,301,805 52.79 8.57 52.76
2017‑02‑13 SC 13G/A INSY / Insys Therapeutics Inc. 4,366,740 6,071,440 39.04 8.46 39.60
2017‑02‑13 SC 13G/A IPXL / Impax Laboratories, Inc. 6,664,100 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A CNXR / Connecture, Inc. 1,740,000 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A DVAX / Dynavax Technologies Corp. 2,472,200 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A ACHN / Achillion Pharmaceuticals, Inc. 9,649,900 13,107,200 35.83 9.59 35.64
2017‑02‑13 SC 13G/A AFFX / Affymetrix, Inc. 7,511,000 0 -100.00 0.0 -100.00
2017‑02‑13 SC 13G/A ARRY / Array BioPharma, Inc. 10,689,000 16,088,800 50.52 9.55 27.50
2017‑02‑13 SC 13G/A CERS / Cerus Corp. 6,504,400 0 -100.00 0.0 -100.00
2017‑02‑07 SC 13D/A ROKA / Roka Bioscience, Inc. 1,464,671 1,464,898 0.02 26.3 -46.44
2017‑02‑03 SC 13G OBSV / Obseva SA 2,559,931 8.64
2017‑01‑27 SC 13D/A AFMD / Affimed N.V. 3,375,000 3,055,000 -9.48 7.06 -30.44
2017‑01‑20 SC 13D/A VRAY / ViewRay, Inc. 9,469,411 9,866,102 4.19 18.8 -16.81
2017‑01‑12 SC 13D/A LOXO / Loxo Oncology, Inc. 1,728,000 1,728,000 0.00 6.76 -15.29
2016‑12‑08 SC 13G/A CYNA / Cynapsus Therapeutics Inc. 816,154 0 -100.00 0.0 -100.00
2016‑12‑01 SC 13D/A RPBIF / Response Biomedical Corp. 6,000,328 0 -100.00 0.0 -100.00
2016‑12‑01 SC 13D/A RPBIF / Response Biomedical Corp. 6,000,328 0 -100.00 0.0 -100.00
2016‑11‑14 SC 13D/A ROKA / Roka Bioscience, Inc. 14,873,637 1,464,671 -90.15 49.1 -2.58
2016‑10‑24 SC 13D/A ASND / Ascendis Pharma AS 3,671,976 4,198,291 14.33 13.3 -8.90
2016‑09‑26 SC 13D/A AFMD / Affimed N.V. 4,053,000 3,375,000 -16.73 10.15 -16.74
2016‑09‑23 SC 13D/A ROKA / Roka Bioscience, Inc. 14,873,637 50.4
2016‑09‑16 SC 13G/A CYNA / Cynapsus Therapeutics Inc. 1,620,325 816,154 -49.63 6.6 -50.00
2016‑08‑26 SC 13D VRAY / ViewRay, Inc. 9,469,411 22.6
2016‑08‑12 SC 13D STDY / SteadyMed Ltd. 3,072,196 14.2
2016‑08‑12 SC 13D/A LOXO / Loxo Oncology, Inc. 2,175,857 1,728,000 -20.58 7.98 -20.52
2016‑08‑05 SC 13D/A LOXO / Loxo Oncology, Inc. 2,175,857 2,175,857 0.00 10.04 -9.71
2016‑07‑28 SC 13D/A RLYP / Relypsa, Inc. 3,356,400 0 -100.00 0.0 -100.00
2016‑07‑26 SC 13D/A RLYP / Relypsa, Inc. 7,400,000 3,356,400 -54.64 7.5 -54.66
2016‑07‑12 SC 13D/A PIRS / Pieris Pharmaceuticals, Inc. 7,259,620 7,259,620 0.00 16.9 -10.11
2016‑07‑08 SC 13G/A CYNA / Cynapsus Therapeutics Inc. 1,227,353 1,620,325 32.02 13.2 32.13
2016‑07‑07 SC 13D SELB / Selecta Biosciences, Inc. 1,842,797 10.3
2016‑06‑30 SC 13D/A ASND / Ascendis Pharma AS 3,300,462 3,671,976 11.26 14.6 11.45
2016‑06‑21 SC 13D/A ASND / Ascendis Pharma AS 3,000,462 3,300,462 10.00 13.1 9.99
2016‑06‑20 SC 13D/A RPBIF / Response Biomedical Corp. 6,000,328 42.6
2016‑06‑20 SC 13D/A RPBIF / Response Biomedical Corp. 6,000,328 42.6
2016‑06‑17 SC 13D/A ASND / Ascendis Pharma AS 2,492,199 3,000,462 20.39 11.91 20.42
2016‑06‑09 SC 13D/A ASND / Ascendis Pharma AS 2,067,199 2,492,199 20.56 9.89 20.46
2016‑06‑07 SC 13D/A ASND / Ascendis Pharma AS 1,703,199 2,067,199 21.37 8.21 21.09
2016‑06‑03 SC 13D/A RLYP / Relypsa, Inc. 7,400,000 7,400,000 0.00 16.54 -6.82
2016‑05‑20 SC 13D NTLA / Intellia Therapeutics, Inc. 2,662,180 7.4
2016‑04‑18 SC 13G AGLE / Aeglea BioTherapeutics, Inc. 1,360,224 10.14
2016‑04‑13 SC 13G/A BITI / Biotie Therapies Corp. 125,382,648 0 -100.00 0.0 -100.00
2016‑04‑01 SC 13D CRVS / Corvus Pharmaceuticals, Inc. 5,258,450 5,258,450 0.00 25.77
2016‑03‑31 SC 13D/A AFMD / Affimed N.V. 4,500,641 4,053,000 -9.95 12.19 -9.90
2016‑03‑17 SC 13D/A AFMD / Affimed N.V. 4,582,616 4,500,641 -1.79 13.53 -12.20
2016‑03‑16 SC 13D/A OTIC / Otonomy, Inc. 1,917,200 1,850,094 -3.50 6.15 -22.25
2016‑02‑16 SC 13G/A IRWD / Ironwood Pharmaceuticals, Inc. 11,226,400 8.84
2016‑02‑16 SC 13G/A XTNT / Xtant Medical Holdings, Inc. 1,267,076 9.99
2016‑02‑16 SC 13G/A CYNA / Cynapsus Therapeutics Inc. 1,216,687 1,227,353 0.88 9.99 0.00
2016‑02‑16 SC 13G IMMU / Immunomedics, Inc. 9,677,008 9.63
2016‑02‑16 SC 13G/A CGNT / Cogentix Medical, Inc. 990,745 3.8
2016‑02‑16 SC 13G/A SGYP / Synergy Pharmaceuticals, Inc. 15,138,384 11.96
2016‑02‑16 SC 13G EHTH / eHealth, Inc. 1,300,000 7.18
2016‑02‑16 SC 13G/A ALBO / Albireo Pharma, Inc. 0 1,133,592 0.00 1.77
2016‑02‑16 SC 13G SRRA / Sierra Oncology 1,989,949 6.62
2016‑02‑16 SC 13G/A FLDM / Fluidigm Corp. 2,628,650 9.07
2016‑02‑16 SC 13G DVAX / Dynavax Technologies Corp. 2,472,200 6.43
2016‑02‑12 SC 13G/A ARRY / Array BioPharma, Inc. 10,689,000 7.49
2016‑02‑12 SC 13G INSM / Insmed, Inc. 3,469,900 5.61
2016‑02‑12 SC 13G/A INFI / Infinity Pharmaceuticals, Inc. 4,416,300 8.97
2016‑02‑12 SC 13G GKOS / Glaukos Corp. 2,897,937 9.03
2016‑02‑12 SC 13G CNXR / Connecture, Inc. 1,740,000 7.89
2016‑02‑12 SC 13G ASMB / Assembly Biosciences, Inc. 1,397,100 8.11
2016‑02‑12 SC 13G INSY / Insys Therapeutics Inc. 4,366,740 6.06
2016‑02‑12 SC 13G IMGN / Immunogen, Inc. 6,095,647 7.01
2016‑02‑12 SC 13G/A AFFX / Affymetrix, Inc. 7,511,000 9.39
2016‑02‑12 SC 13G ACHN / Achillion Pharmaceuticals, Inc. 9,649,900 7.07
2016‑02‑12 SC 13G/A CERS / Cerus Corp. 6,504,400 6.7
2016‑02‑12 SC 13G/A ARQL / ArQule, Inc. 0 0 0.00 0.0
2016‑02‑12 SC 13G/A IPXL / Impax Laboratories, Inc. 6,664,100 9.45
2016‑02‑11 SC 13G/A PRQR / ProQR Therapeutics N.V. 2,271,500 9.73
2016‑02‑11 SC 13G MGLN / Magellan Health, Inc. 1,833,000 7.17
2016‑02‑11 SC 13G/A NBIX / Neurocrine Biosciences, Inc. 2,514,974 2.92
2016‑02‑11 SC 13G/A MRTX / Mirati Therapeutics, Inc. 376,999 1.92
2016‑02‑11 SC 13G/A SIEN / Sientra, Inc. 1,357,500 7.54
2016‑02‑11 SC 13G/A WMGIZ / Wright Medical Group N.V. 8,245,111 8.03
2016‑02‑11 SC 13G/A NSPR / InspireMD, Inc. 0 0 0.00 0.0
2016‑02‑11 SC 13G OPHT / Ophthotech Corp 2,011,500 5.75
2016‑02‑11 SC 13G PBYI / Puma Biotechnology Inc. 2,238,825 6.9
2016‑02‑11 SC 13G/A MEIP / MEI Pharma, Inc. 0 0.0
2016‑02‑11 SC 13G/A MOH / Molina Healthcare, Inc. 568,850 1.01
2016‑02‑11 SC 13G/A XNPT / XenoPort, Inc. 5,768,400 9.13
2016‑02‑11 SC 13G/A SVA / Sinovac Biotech Ltd. 2,667,500 4.78
2015‑12‑24 SC 13D/A RLYP / Relypsa, Inc. 7,900,000 7,400,000 -6.33 17.75 -6.58
2015‑11‑25 SC 13D/A OTIC / Otonomy, Inc. 1,917,200 7.91
2015‑11‑20 SC 13D/A ASND / Ascendis Pharma AS 26,467,120 1,703,199 -93.56 6.78 9.35
2015‑11‑19 SC 13D/A ADAP / Adaptimmune Therapeutics plc 28,041,004 6.6
2015‑11‑19 SC 13D/A LOXO / Loxo Oncology, Inc. 2,175,857 11.12
2015‑11‑06 SC 13D DMTX / Dimension Therapeutics, Inc. 5,397,698 21.7
2015‑10‑30 SC 13D/A RLYP / Relypsa, Inc. 7,400,000 7,900,000 6.76 19.0 6.44
2015‑10‑02 SC 13D NBRV / Nabriva Therapeutics AG 307,179 14.52
2015‑09‑04 SC 13G/A BITI / Biotie Therapies Corp. 73,438,204 125,382,648 70.73 12.14 62.08
2015‑08‑17 SC 13D/A AFMD / Affimed N.V. 5,814,630 4,582,616 -21.19 15.41 -21.22
2015‑07‑09 SC 13D PIRS / Pieris Pharmaceuticals, Inc. 7,259,620 18.8
2015‑07‑02 SC 13G CYNA / Cynapsus Therapeutics Inc. 1,216,687 9.99
2015‑06‑26 SC 13G BITI / Biotie Therapies Corp. 73,438,204 7.49
2015‑05‑20 SC 13D/A RLYP / Relypsa, Inc. 7,400,000 17.85
2015‑05‑15 SC 13D ASND / Ascendis Pharma AS 26,467,120 6.2
2015‑05‑14 SC 13D/A AFMD / Affimed N.V. 5,814,630 19.56
2015‑03‑30 SC 13D/A ICPT / Intercept Pharmaceuticals, Inc. 1,120,324 4.95
2015‑03‑25 SC 13D/A ICPT / Intercept Pharmaceuticals, Inc. 1,277,524 5.64
2015‑03‑09 SC 13G SGYP / Synergy Pharmaceuticals, Inc. 14,857,736 13.57
2015‑03‑06 SC 13D/A RLYP / Relypsa, Inc. 8,857,551 21.6