InvestorPerceptive Advisors Llc
ManagerJoseph Edelman
Insider ProfilePERCEPTIVE ADVISORS LLC
Portfolio Value $ 3,016,759,000
Current Positions130
Opened Positions5
Closed Positions44


Latest Holdings, Performance, AUM (from 13F, 13D)

Perceptive Advisors Llc has disclosed 130 total holdings in their latest SEC filings. Portfolio manager(s) are listed as Joseph Edelman. Most recent portfolio value is calculated to be $ 3,016,759,000 USD. Actual Assets Under Management (AUM) is this value plus cash (which is not disclosed).

Top Holdings

Perceptive Advisors Llc's top holdings are Neurocrine Biosciences, Inc. (NASDAQ:NBIX) , Amicus Therapeutics, Inc. (NASDAQ:FOLD) , Global Blood Therapeutics, Inc. (NASDAQ:GBT) , Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) , and Zogenix, Inc. (NASDAQ:ZGNX) . Perceptive Advisors Llc's new positions include Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) , Synta Pharmaceuticals, Inc. (NASDAQ:SNTA) , Revance Therapeutics, Inc. (NASDAQ:RVNC) , ANI Pharmaceuticals, Inc. 3% Convertible Bond (00182CAA1) , and Flexion Therapeutics, Inc. (NASDAQ:FLXN) . Perceptive Advisors Llc's top industries are "Apparel And Accessory Stores" (sic 56) , "Security And Commodity Brokers, Dealers, Exchanges, And Services" (sic 62) , and "Rubber And Miscellaneous Plastics Products" (sic 30) .

All Perceptive Advisors Llc holdings are listed in the following tables. Data is sourced from 13D/13G, 13F, and N-Q filings. Green rows indicate new positions. Red rows indicate closed positions.

This is a list of 13D and 13G filings made since the last quarterly 13F report (if any). Click the link icon to see the full transaction history.

File DateFormSecurity Prev
Shares
Current
Shares
Change
(Percent)
Ownership
Change
(Percent)
2018‑02‑14 SC 13G/A ABEO / Abeona Therapeutics Inc. 2,101,809 1,319,298 -37.23 2.80 -46.56
2018‑02‑14 SC 13G/A DOVA / Dova Pharmaceuticals, Inc. 1,809,015 7.10
2018‑02‑14 SC 13G/A OMED / OncoMed Pharmaceuticals, Inc. 2,470,897 2,620,897 6.07 6.90 6.15
2018‑02‑14 SC 13G/A PSDV / pSivida Corp. 2,279,706 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A CTMX / CytomX Therapeutics, Inc. 2,165,381 2,490,381 15.01 6.50 16.07
2018‑02‑14 SC 13G/A AVDL / Avadel Pharmaceuticals plc 2,391,841 6.00
2018‑02‑14 SC 13G/A ALQA / Alliqua, Inc. 1,921,951 429,108 -77.67 8.60 27.60
2018‑02‑14 SC 13G/A FOLD / Amicus Therapeutics, Inc. 17,296,672 17,888,597 3.42 10.80 -10.74
2018‑02‑14 SC 13G/A NBIX / Neurocrine Biosciences, Inc. 4,657,589 5,151,589 10.61 5.80 9.43
2018‑02‑14 SC 13G/A KDMN / Kadmon Holdings, Inc. 5,185,847 6,356,221 22.57 8.00 -20.00
2018‑02‑14 SC 13G/A ZGNX / Zogenix, Inc. 3,448,302 3,970,357 15.14 11.60 -16.49
2018‑02‑14 SC 13G/A SRRA / Sierra Oncology 3,655,186 5,000,000 36.79 9.60 37.14
2018‑02‑14 SC 13G/A DBVT / DBV Technologies S.A. 1,297,350 1,426,772 9.98 5.70 9.62
2018‑02‑14 SC 13G/A NEPT / Neptune Technologies & Bioressources Inc. 8,050,315 8,374,015 4.02 10.60 3.92
2018‑02‑14 SC 13G/A VSAR / Versartis, Inc.. 2,099,563 1,488,160 -29.12 4.20 -28.81
2018‑02‑14 SC 13G/A ACRS / Aclaris Therapeutics, Inc. 1,260,847 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A OCRX / Ocera Therapeutics, Inc. 2,150,000 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A ADMP / Adamis Pharmaceuticals Corp. 1,500,000 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A ZYNE / Zynerba Pharmaceuticals, Inc. 842,128 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A MGCD / MGC Diagnostics Corp. 329,733 0 -100.00 0.00 -100.00
2018‑02‑14 SC 13G/A ALDX / Aldeyra Therapeutics,Inc. 1,940,458 3,085,458 59.01 16.10 4.55
2018‑02‑14 SC 13G/A IOVA / Iovance Biotherapeutics Inc. 3,567,553 3,091,903 -13.33 4.30 -25.09
2018‑02‑14 SC 13G/A QURE / uniQure N.V. 1,265,963 1,047,950 -17.22 3.40 -32.41
2018‑02‑14 SC 13G/A CORI / Corium International, Inc. 3,847,133 5,847,133 51.99 16.20 23.10
2018‑01‑26 SC 13G HSGX / Histogenics Corporation 2,203,277 8.80
2018‑01‑09 SC 13G AGRX / Agile Therapeutics, Inc. 3,380,000 9.90

This form was filed on February 14, 2018. Click the link icon to see the full transaction history.

Reporting PeriodFormSecurity Imputed
Share Price
Prev SharesCurrent SharesChange
(Percent)
Prev Value ($K)Current Value ($K)Change
(Percent)
2017-12-31 13F-HR ABYLY / Ablynx NV 24.99 250,000 6,248
2017-12-31 13F-HR ACER / Acer Therapeutics Inc. 13.94 150,000 2,091
2017-12-31 13F-HR ACHN / Achillion Pharmaceuticals, Inc. 2.88 0 1,000,000 0 2,880
2017-12-31 13F-HR ALNA / Allena Pharmaceuticals, Inc. 10.06 250,000 2,515
2017-12-31 13F-HR ALLIQUA BIOMEDICAL INC / (019621309) 1.81 423,394 766
2017-12-31 13F-HR CDNA / CareDx, Inc. 7.34 1,040,676 7,639
2017-12-31 13F-HR CASI / CASI Pharmaceuticals, Inc. 3.25 83,682 272
2017-12-31 13F-HR CLLS / Cellectis S.A. 29.15 0 350,000 0 10,203
2017-12-31 13F-HR FLXN / Flexion Therapeutics, Inc. 25.04 307,989 7,712
2017-12-31 13F-HR ISRG / Intuitive Surgical, Inc. 364.94 25,195 70,585 180.15 26,351 25,759 -2.25
2017-12-31 13F-HR JUNO / Juno Therapeutics, Inc. Call 0.31 300,000 93
2017-12-31 13F-HR SNTA / Synta Pharmaceuticals, Inc. 91.79 188,893 17,338
2017-12-31 13F-HR ODT / Odonate Therapeutics, Inc. 25.00 150,000 3,750
2017-12-31 13F-HR MRTX / Mirati Therapeutics, Inc. 18.25 0 29,091 0 531
2017-12-31 13F-HR 71426VAK4 / Pernix Therapeutics Holdings, Inc. Convertible Debt 4.25% 420 421 0.24
2017-12-31 13F-HR RVNC / Revance Therapeutics, Inc. 35.75 400,000 14,300
2017-12-31 13F-HR RYTM / Rhythm Pharmaceuticals, Inc. 29.06 745,135 21,654
2017-12-31 13F-HR SPPI / Spectrum Pharmaceuticals, Inc. 18.94 32,154 609
2017-12-31 13F-HR VRX / Valeant Pharmaceuticals International, Inc. 20.77 30,092 625
2017-12-31 13F-HR HCM / Hutchison China MediTech Limited 39.40 10,000 10,000 0.00 273 394 44.32
2017-12-31 13F-HR XBI / SPDR S&P Biotech ETF Put 0.96 0 600,000 0 579
2017-12-31 13F-HR WVE / WAVE Life Sciences Ltd. 35.10 642,798 662,798 3.11 13,980 23,264 66.41
2017-12-31 13F-HR NVTA / Invitae Corp. 9.08 1,884,500 2,004,500 6.37 17,657 18,200 3.08
2017-12-31 13F-HR GLPG / Galapagos N.V. 93.76 206,405 206,305 -0.05 21,002 19,343 -7.90
2017-12-31 13F-HR AKBA / Akebia Therapeutics, Inc. 14.87 1,630,000 1,987,400 21.93 32,062 29,553 -7.83
2017-12-31 13F-HR CAPR / Capricor Therapeutics, Inc. 1.50 0 4,000 0 6
2017-12-31 13F-HR SCMP / Sucampo Pharmaceuticals, Inc. 17.95 0 40,062 0 719
2017-12-31 13F-HR NBIX / Neurocrine Biosciences, Inc. 77.59 4,791,589 5,151,589 7.51 293,629 399,712 36.13
2017-12-31 13F-HR CTMX / CytomX Therapeutics, Inc. 21.11 1,390,381 2,490,381 79.12 25,263 52,571 108.09
2017-12-31 13F-HR CRBP / Corbus Pharmaceuticals Holdings, Inc. 7.10 414,684 200,000 -51.77 2,964 1,420 -52.09
2017-12-31 13F-HR ASMB / Assembly Biosciences, Inc. 45.25 441,833 536,626 21.45 15,429 24,282 57.38
2017-12-31 13F-HR ADMA / ADMA Biologics Inc 3.21 721,102 3,821,102 429.90 2,221 12,266 452.27
2017-12-31 13F-HR BCLI / BrainStorm Cell Therapeutics Inc. 3.92 400,000 400,000 0.00 1,648 1,568 -4.85
2017-12-31 13F-HR ARGX / argenx SE ADS 63.14 450,000 537,361 19.41 10,098 33,929 236.00
2017-12-31 13F-HR VNDA / Vanda Pharmaceuticals, Inc. 36,232 0 -100.00 649 0 -100.00
2017-12-31 13F-HR PRAH / PRA Health Sciences, Inc. 7,427 0 -100.00 566 0 -100.00
2017-12-31 13F-HR RGEN / Repligen Corp. 87,400 0 -100.00 3,349 0 -100.00
2017-12-31 13F-HR OSUR / OraSure Technologies, Inc. 54,729 0 -100.00 1,231 0 -100.00
2017-12-31 13F-HR INOV / Inovalon Holdings, Inc. 30,000 0 -100.00 511 0 -100.00
2017-12-31 13F-HR IONS / Ionis Pharmaceuticals, Inc. Call 60,000 0 -100.00 24 0 -100.00
2017-12-31 13F-HR NXTM / NxStage Medical, Inc. 1,264,523 0 -100.00 34,901 0 -100.00
2017-12-31 13F-HR ATRA / Atara Biotherapeutics, Inc. 35,106 0 -100.00 581 0 -100.00
2017-12-31 13F-HR AKAO / Achaogen, Inc. 27,551 0 -100.00 439 0 -100.00
2017-12-31 13F-HR MOH / Molina Healthcare, Inc. Call 50,000 0 -100.00 345 0 -100.00
2017-12-31 13F-HR ONCE / Spark Therapeutics, Inc. 180,000 0 -100.00 16,049 0 -100.00
2017-12-31 13F-HR DBVT / DBV Technologies S.A. Put 550,000 0 -100.00 2,808 0 -100.00
2017-12-31 13F-HR EXAS / EXACT Sciences Corp. 135,444 0 -100.00 6,382 0 -100.00
2017-12-31 13F-HR ALQA / Alliqua, Inc. 4,233,951 0 -100.00 15,458 0 -100.00
2017-12-31 13F-HR ABMD / ABIOMED, Inc. 187.41 51,729 215,000 315.63 8,722 40,293 361.97
2017-12-31 13F-HR ACST / Acasti Pharma, Inc. 0.94 186,559 186,559 0.00 267 176 -34.08
2017-12-31 13F-HR BIOD / Biodel, Inc. 25.60 845,000 1,320,000 56.21 17,703 33,792 90.88
2017-12-31 13F-HR AFMD / Affimed N.V. 1.30 668,214 668,214 0.00 1,503 869 -42.18
2017-12-31 13F-HR AGRX / Agile Therapeutics, Inc. 2.69 0 3,380,000 0 9,092
2017-12-31 13F-HR 00182CAA1 / ANI Pharmaceuticals, Inc. 3% Convertible Bond 8,119 8,642 6.44
2017-12-31 13F-HR ARNA / Arena Pharmaceuticals, Inc. 33.99 21,978 747
2017-12-31 13F-HR ANAB / AnaptysBio, Inc. 100.72 982,269 756,387 -23.00 34,330 76,183 121.91
2017-12-31 13F-HR FOLD / Amicus Therapeutics, Inc. 14.39 17,888,597 17,888,597 0.00 269,760 257,417 -4.58
2017-12-31 13F-HR AMGN / Amgen Inc. 173.90 0 50,000 0 8,695
2017-12-31 13F-HR ALGN / Align Technology, Inc. 222.16 3,448 3,448 0.00 642 766 19.31
2017-12-31 13F-HR ALDX / Aldeyra Therapeutics,Inc. 6.80 3,085,458 3,085,458 0.00 22,215 20,981 -5.55
2017-12-31 13F-HR ALNY / Alnylam Pharmaceuticals, Inc. 127.05 1,788,802 1,330,802 -25.60 210,167 169,079 -19.55
2017-12-31 13F-HR CSU / Capital Senior Living Corp. 13.49 560,173 680,173 21.42 7,031 9,176 30.51
2017-12-31 13F-HR BOLD / Audentes Therapeutics, Inc. 31.25 781,309 781,309 0.00 21,885 24,416 11.56
2017-12-31 13F-HR BPMC / Blueprint Medicines Corporation 75.41 424,661 1,140,434 168.55 29,586 86,000 190.68
2017-12-31 13F-HR BLUE / bluebird bio, Inc. 178.12 0 14,400 0 2,565
2017-12-31 13F-HR AVXS / AveXis, Inc. 110.67 671,181 480,141 -28.46 64,923 53,137 -18.15
2017-12-31 13F-HR AVEO / AVEO Pharmaceuticals, Inc. 2.79 3,415,116 2,958,116 -13.38 12,555 8,253 -34.27
2017-12-31 13F-HR BHVN / Biohaven Pharmaceutical Holding 26.98 306,134 261,134 -14.70 11,443 7,045 -38.43
2017-12-31 13F-HR CORI / Corium International, Inc. 9.61 5,847,133 5,847,133 0.00 64,786 56,191 -13.27
2017-12-31 13F-HR CRIS / Curis, Inc. 0.70 951,201 951,201 0.00 1,417 666 -53.00
2017-12-31 13F-HR CLDN / Celladon Corporation 13.95 157,679 157,679 0.00 1,734 2,199 26.82
2017-12-31 13F-HR CBAY / Cymabay Therapeutics Inc. 9.20 2,350,882 2,685,882 14.25 18,948 24,710 30.41
2017-12-31 13F-HR DCPH / Deciphera Pharmaceuticals, Inc. 22.67 102,500 102,500 0.00 1,946 2,324 19.42
2017-12-31 13F-HR DBVT / DBV Technologies S.A. 24.60 576,419 978,619 69.78 24,463 24,075 -1.59
2017-12-31 13F-HR EXEL / Exelixis, Inc. 30.39 46,361 46,361 0.00 1,123 1,409 25.47
2017-12-31 13F-HR CUTR / Cutera, Inc. 45.32 11,981 11,981 0.00 495 543 9.70
2017-12-31 13F-HR CLSD / Clearside Biomedical, Inc. 7.00 620,181 620,181 0.00 5,147 4,341 -15.66
2017-12-31 13F-HR ESPR / Esperion Therapeutics, Inc. 65.84 10,769 10,769 0.00 540 709 31.30
2017-12-31 13F-HR FCAU / Fiat Chrysler Automobiles N.V 17.84 62,000 62,000 0.00 1,110 1,106 -0.36
2017-12-31 13F-HR FOMX / Foamix Pharmaceuticals Ltd. 6.01 1,117,324 1,117,324 0.00 6,201 6,715 8.29
2017-12-31 13F-HR RXDX / Ignyta, Inc. 26.71 0 30,211 0 807
2017-12-31 13F-HR HSGX / Histogenics Corporation 2.05 1,777,777 1,777,777 0.00 3,519 3,644 3.55
2017-12-31 13F-HR GMED / Globus Medical, Inc. 41.10 0 113,100 0 4,648
2017-12-31 13F-HR HUM / Humana, Inc. 248.06 100,000 77,500 -22.50 24,363 19,225 -21.09
2017-12-31 13F-HR IRTC / iRhythm Technologies, Inc. 56.05 372,671 427,371 14.68 19,335 23,954 23.89
2017-12-31 13F-HR KDMN / Kadmon Holdings, Inc. 3.62 5,185,847 5,185,847 0.00 17,372 18,772 8.06
2017-12-31 13F-HR LNTH / Lantheus Holdings, Inc. 20.44 53,763 53,763 0.00 957 1,099 14.84
2017-12-31 13F-HR MMSI / Merit Medical Systems, Inc. 43.20 100,000 874,013 774.01 4,235 37,757 791.55
2017-12-31 13F-HR LJPC / La Jolla Pharmaceutical Co. 32.18 2,157,011 3,388,611 57.10 75,021 109,046 45.35
2017-12-31 13F-HR KERX / Keryx Biopharmaceuticals, Inc. 4.65 83,386 83,386 0.00 592 388 -34.46
2017-12-31 13F-HR NLNK / NewLink Genetics Corp 8.11 450,000 450,000 0.00 4,581 3,650 -20.32
2017-12-31 13F-HR THLD / Threshold Pharmaceuticals, Inc. 10.02 724,133 724,133 0.00 4,231 7,255 71.47
2017-12-31 13F-HR NEOS / Neos Therapeutics, Inc. 10.20 0 300,000 0 3,060
2017-12-31 13F-HR PGNX / Progenics Pharmaceuticals, Inc. 5.95 61,850 368
2017-12-31 13F-HR QTRX / Quanterix Corporation 21.47 169,400 3,637
2017-12-31 13F-HR REGN / Regeneron Pharmaceuticals, Inc. 375.95 20,000 7,519
2017-12-31 13F-HR OXFD / Oxford Immunotec Global PLC 13.97 465,356 500,356 7.52 7,818 6,990 -10.59
2017-12-31 13F-HR QTNT / Quotient Limited 4.92 3,726,986 6,033,020 61.87 18,374 29,683 61.55
2017-12-31 13F-HR PBYI / Puma Biotechnology Inc. 98.85 923,820 703,820 -23.81 110,627 69,573 -37.11
2017-12-31 13F-HR PBYI / Puma Biotechnology Inc. Call 0.55 0 100,000 0 55
2017-12-31 13F-HR OMED / OncoMed Pharmaceuticals, Inc. 4.10 1,038,289 2,620,897 152.42 4,693 10,745 128.96
2017-12-31 13F-HR PFNX / Pfenex Inc. 2.66 845,973 519,773 -38.56 2,555 1,383 -45.87
2017-12-31 13F-HR RGNX / REGENXBIO Inc. 33.25 1,441,186 1,421,186 -1.39 47,487 47,254 -0.49
2017-12-31 13F-HR SELB / Selecta Biosciences, Inc. 9.81 1,162,325 632,712 -45.56 21,212 6,206 -70.74
2017-12-31 13F-HR RTRX / Retrophin, Inc. 21.07 2,686,204 2,672,525 -0.51 66,859 56,310 -15.78
2017-12-31 13F-HR SBBP / Strongbridge Biopharma plc 7.25 275,000 1,994
2017-12-31 13F-HR SRRA / Sierra Oncology 3.73 3,655,186 5,000,000 36.79 5,666 18,650 229.16
2017-12-31 13F-HR MIRN / Mirna Therapeutics, Inc. 9.70 686,352 686,352 0.00 13,050 6,658 -48.98
2017-12-31 13F-HR SENS / Senseonics Holdings, Inc. 2.66 50,000 115,000 130.00 160 306 91.25
2017-12-31 13F-HR VBI VACCINES INC / (91822J103) 4.27 9,665,843 41,273
2017-12-31 13F-HR VICL / Vical Inc. 1.83 1,142,858 2,091
2017-12-31 13F-HR VRAY / ViewRay, Inc. 9.26 50,000 463
2017-12-31 13F-HR TFX / Teleflex, Inc. 248.82 55,200 125,900 128.08 13,357 31,326 134.53
2017-12-31 13F-HR QURE / uniQure N.V. 19.59 1,040,119 1,047,950 0.75 9,985 20,529 105.60
2017-12-31 13F-HR TSRO / TESARO, Inc. 82.87 388,651 129,372 -66.71 50,175 10,721 -78.63
2017-12-31 13F-HR VSAR / Versartis, Inc.. 2.20 1,888,160 1,488,160 -21.18 4,625 3,273 -29.23
2017-12-31 13F-HR VRNA / Verona Pharma plc 11.92 200,000 200,000 0.00 3,070 2,384 -22.35
2017-12-31 13F-HR URGN / Urogen Pharma Ltd. 37.21 269,014 199,014 -26.02 8,479 7,405 -12.67
2017-12-31 13F-HR ZYME / Zymeworks Inc 7.14 730,768 777,497 6.39 5,832 5,549 -4.85
2017-12-31 13F-HR ZGNX / Zogenix, Inc. 40.50 3,670,357 3,970,357 8.17 128,646 160,799 24.99
2017-12-31 13F-HR ZSAN / Zosano Pharma Corporation 0.52 500,000 500,000 0.00 412 260 -36.89
2017-12-31 13F-HR ZBH / Zimmer Biomet Holdings, Inc 120.67 0 200,000 0 24,134
2017-12-31 13F-HR ZLAB / Zai Lab Limited 21.23 175,000 175,000 0.00 4,725 3,715 -21.38
2017-12-31 13F-HR XNCR / Xencor, Inc. 21.92 1,293,095 1,313,095 1.55 29,638 28,783 -2.88
2017-12-31 13F-HR VCRA / Vocera Communications, Inc. 30.23 0 35,169 0 1,063
2017-12-31 13F-HR MRNS / Marinus Pharmaceuticals, Inc. 8.16 1,452,700 907,732 -37.51 8,527 7,407 -13.13
2017-12-31 13F-HR MYOK / MyoKardia, Inc. 42.10 550,717 710,726 29.05 23,598 29,922 26.80
2017-12-31 13F-HR RACE / Ferrari N.V. 104.84 6,200 6,200 0.00 685 650 -5.11
2017-12-31 13F-HR FLML / Flamel Technologies S.A. 8.20 1,549,005 2,391,841 54.41 16,265 19,613 20.58
2017-12-31 13F-HR DOVA / Dova Pharmaceuticals, Inc. 28.80 1,754,015 1,809,015 3.14 42,587 52,099 22.34
2017-12-31 13F-HR IVCRB / Invacare Corp. 16.85 200,000 200,000 0.00 3,950 3,370 -14.68
2017-12-31 13F-HR EVH / Evolent Health Inc. 12.30 850,000 50,000 -94.12 15,130 615 -95.94
2017-12-31 13F-HR ABEOW / Abeona Therapeutics Inc. Warrants 11.60 1,259,636 1,259,636 0.00 15,846 14,612 -7.79
2017-12-31 13F-HR CNC / Centene Corp. 100.91 7,726 6,699 -13.29 748 676 -9.63
2017-12-31 13F-HR IOVA / Iovance Biotherapeutics Inc. 8.00 4,726,114 4,776,114 1.06 36,627 38,208 4.32
2017-12-31 13F-HR ECYT / Endocyte, Inc. 4.28 0 1,451,700 0 6,213
2017-12-31 13F-HR XLRN / Acceleron Pharma Inc. 42.44 1,616,259 1,616,259 0.00 60,319 68,594 13.72
2017-12-31 13F-HR ATRS / Antares Pharma, Inc. 1.99 4,353,897 3,745,662 -13.97 14,107 7,454 -47.16
2017-12-31 13F-HR VRTX / Vertex Pharmaceuticals Inc. 149.86 138,626 138,626 0.00 21,077 20,774 -1.44
2017-12-31 13F-HR AZRX / AzurRx BioPharma, Inc. 3.70 227,272 227,272 0.00 907 841 -7.28
2017-12-31 13F-HR PRTO / Proteon Therapeutics, Inc. 1.90 334,116 334,116 0.00 668 635 -4.94
2017-12-31 13F-HR CSBR / Champions Oncology, Inc. 3.88 386,540 386,540 0.00 1,418 1,499 5.71
2017-12-31 13F-HR BGNE / BeiGene, Ltd. 97.72 5,700 5,700 0.00 590 557 -5.59
2017-12-31 13F-HR ABEO / Abeona Therapeutics Inc. 15.86 116,900 59,662 -48.96 1,993 946 -52.53
2017-12-31 13F-HR GBT / Global Blood Therapeutics, Inc. 39.35 4,264,066 4,889,066 14.66 132,399 192,384 45.31
2017-12-31 13F-HR NEPT / Neptune Technologies & Bioressources Inc. 2.36 6,519,634 8,374,015 28.44 4,113 19,762 380.48
2017-12-31 13F-HR NUCANA PLS / SPONSORED ADR (67022C106) 200,000 0 -100.00 3,674 0
2017-12-31 13F-HR SAGE / Sage Therapeutics, Inc. Call 215,000 0 -100.00 178 0 -100.00
2017-12-31 13F-HR ARDX / Ardelyx, Inc. 1,352,391 0 -100.00 7,573 0 -100.00
2017-12-31 13F-HR MGCD / MGC Diagnostics Corp. 252,327 0 -100.00 2,261 0 -100.00
2017-12-31 13F-HR ATHN / athenahealth, Inc. 70,000 0 -100.00 8,705 0 -100.00
2017-12-31 13F-HR PTLA / Portola Pharmaceuticals, Inc. 7,870 0 -100.00 425 0 -100.00
2017-12-31 13F-HR ACRX / AcelRx Pharmaceuticals, Inc. 1,244,608 0 -100.00 5,725 0 -100.00
2017-12-31 13F-HR XENE / Xenon Pharmaceuticals Inc. 503,853 0 -100.00 1,486 0 -100.00
2017-12-31 13F-HR GWPH / GW Pharmaceuticals Plc. 36,763 0 -100.00 3,731 0 -100.00
2017-12-31 13F-HR INCY / Incyte Corp. 5,619 0 -100.00 656 0 -100.00
2017-12-31 13F-HR INCY / Incyte Corp. Call 100,000 0 -100.00 35 0 -100.00
2017-12-31 13F-HR HRTX / Heron Therapeutics, Inc. 330,000 0 -100.00 5,329 0 -100.00
2017-12-31 13F-HR TDOC / Teladoc, Inc. 14,641 0 -100.00 485 0 -100.00
2017-12-31 13F-HR HSKA / Heska Corp. 7,300 0 -100.00 643 0 -100.00
2017-12-31 13F-HR OCRX / Ocera Therapeutics, Inc. 2,038,880 0 -100.00 2,324 0 -100.00
2017-12-31 13F-HR ICPT / Intercept Pharmaceuticals, Inc. 90,000 0 -100.00 5,224 0 -100.00
2017-12-31 13F-HR ICPT / Intercept Pharmaceuticals, Inc. Call 250,000 0 -100.00 283 0 -100.00
2017-12-31 13F-HR MCRB / Seres Therapeutics, Inc. 135,000 0 -100.00 2,165 0 -100.00
2017-12-31 13F-HR VYGR / Voyager Therapeutics, Inc 34,604 0 -100.00 712 0 -100.00
2017-12-31 13F-HR ZYNE / Zynerba Pharmaceuticals, Inc. 130,700 0 -100.00 1,320 0 -100.00
2017-12-31 13F-HR IMGN / Immunogen, Inc. 70,126 0 -100.00 536 0 -100.00
2017-12-31 13F-HR ITCI / Intra-Cellular Therapies Inc. 929,460 0 -100.00 14,667 0 -100.00
2017-12-31 13F-HR VIVMF / Viveve Medical, Inc. 486,988 0 -100.00 2,551 0 -100.00
2017-12-31 13F-HR ALNY / Alnylam Pharmaceuticals, Inc. Call 100,000 0 -100.00 2,315 0 -100.00
2017-12-31 13F-HR ALNY / Alnylam Pharmaceuticals, Inc. Put 420,000 0 -100.00 45 0 -100.00
2017-12-31 13F-HR GILD / Gilead Sciences, Inc. 40,000 0 -100.00 3,241 0 -100.00
2017-12-31 13F-HR NBRV / Nabriva Therapeutics AG 52,570 0 -100.00 431 0 -100.00
2017-12-31 13F-HR PRTK / Paratek Pharmaceuticals, Inc. 21,186 0 -100.00 532 0 -100.00
2017-12-31 13F-HR CMTA / Clementia Pharmaceuticals Inc. 352,250 0 -100.00 6,291 0 -100.00
2017-12-31 13F-HR FGEN / FibroGen, Inc. 8,593 0 -100.00 462 0 -100.00